Evidence map›Paper›PMID 40747741›Full record

ArticleThe Laryngoscope2025

Risk Analysis Index Versus Modified Frailty Index: Outcomes After Otolaryngologic Surgery.

Lauran K Evans, Carine Tamamian, Desiree Delavary, Matthew E Lin, Hong-Ho Yang, Maie St John, Dinesh K Chhetri

Abstract readComparative Study
In one paragraph

Article in The Laryngoscope, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lauran K EvansDepartment of Head and Neck Surgery, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, USA.ORCID 0000-0002-9860-5248
Carine TamamianSan Diego School of Medicine, University of California, La Jolla, California, USA.
Desiree DelavaryA.T. Still University School of Osteopathic Medicine, Mesa, Arizona, USA.
Matthew E LinDepartment of Head and Neck Surgery, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, USA.ORCID 0000-0001-9914-9670
Hong-Ho YangDepartment of Otolaryngology-Head and Neck Surgery, Stanford University, Palo Alto, California, USA.ORCID 0000-0003-2032-3141
Maie St JohnDepartment of Head and Neck Surgery, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, USA.ORCID 0000-0001-7068-9534
Dinesh K ChhetriDepartment of Head and Neck Surgery, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePatient frailty negatively impacts postsurgical outcomes across multiple specialties. Commonly used frailty scoring systems include the Modified 5-Item Frailty Index (MFI-5) and the Clinical Risk Analysis Index (RAI-C). We compared these frailty indices in predicting postsurgical outcomes in otolaryngology, a comparison that has never been completed to date.

methodsRetrospective chart review of patients undergoing otolaryngologic surgery at a quaternary care medical center (2022-2024) with an RAI-C score available for analysis. Chi-square analysis and ROC curves were utilized to determine associations and predictive ability of each scoring system.

resultsAmong 1209 patients, 21% met MFI-5 frailty criteria (MFI-5 score > 1), and 23% met RAI-C frailty criteria (RAI-C score > 30). The Pearson correlation coefficient between MFI-5 and RAI-C was 0.481 (95% CI [0.43, 0.53]), indicating a moderate correlation between the two metrics. Patients deemed frail by RAI-C had 5.7 times higher odds of experiencing a postoperative complication than non-frail counterparts (95% CI [3.51, 9.28], p < 0.0001), but MFI-5 frailty status was not associated with postoperative complications. Both RAI-C and MFI-5 demonstrated significant predictive ability for 30-day readmission (AUC 0.77, 95% CI [0.64, 0.89] vs. AUC 0.76, 95% CI [0.61, 0.88]), respectively. When compared to MFI-5, RAI-C had greater predictive performance for all other postoperative outcomes in this study.

conclusionRAI-C outperformed MFI-5 in predicting postoperative outcomes in patients undergoing otolaryngologic surgeries. RAI-C assessment should be considered in frailty research, multidisciplinary treatment planning, and managing patient expectations and outcomes.

Indexed as

FrailtyOtorhinolaryngologic Surgical ProceduresPostoperative ComplicationsAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesRisk AssessmentROC CurvefrailtyMFI‐5postoperative complicationsRAI‐Csurgical outcomes

Identifiers

PMID40747741
PMCPMC12706550

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.