Evidence map›Paper›PMID 40747717›Full record

ReviewOncology reports2025

Role of miRNA‑214‑3p in cancer (Review).

Zeshan Chen, Xin Deng, Yuanhong Lu, Ling Lu, Yijue Qin, Haishun Qu, Shaohang Lan

Abstract readReview
In one paragraph

Review in Oncology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zeshan ChenDepartment of Traditional Chinese Medicine, Guangxi Zhuang Autonomous Region People's Hospital, Nanning, Guangxi 530016, P.R. China.
Xin DengSchool of Basic Medical Sciences, Guangxi University of Traditional Chinese Medicine, Nanning, Guangxi 530200, P.R. China.
Yuanhong LuDepartment of Traditional Chinese Medicine, Guangxi Zhuang Autonomous Region People's Hospital, Nanning, Guangxi 530016, P.R. China.
Ling LuDepartment of Traditional Chinese Medicine, Guangxi Zhuang Autonomous Region People's Hospital, Nanning, Guangxi 530016, P.R. China.
Yijue QinDepartment of Traditional Chinese Medicine, Guangxi Zhuang Autonomous Region People's Hospital, Nanning, Guangxi 530016, P.R. China.
Haishun QuDepartment of Traditional Chinese Medicine, Guangxi Zhuang Autonomous Region People's Hospital, Nanning, Guangxi 530016, P.R. China.
Shaohang LanDepartment of Traditional Chinese Medicine, Guangxi Zhuang Autonomous Region People's Hospital, Nanning, Guangxi 530016, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

microRNA‑214‑3p (miRNA‑214‑3p) can be mapped to the human chromosome 1q24.3 and is ~22 nucleotides in length. It has been garnering considerable attention due to its aberrant expression profile in various different types of cancer and its apparent role in regulating tumor progression. In malignant tumors, miRNA‑214‑3p can serve as a tumor suppressor or oncogene. This can be mediated by mainly inhibiting the expression of target genes by binding to the 3'‑untranslated region of target mRNAs, thereby regulating multiple downstream cellular processes, such as cell proliferation, metastasis, invasion and apoptosis. However, the role of miRNA‑214‑3p in cancer remains unclear. Therefore, in the present review, the role of miRNA‑214‑3p in cancer was summarized, whilst analyzing its potential as a biomarker for cancer diagnosis, prognosis and response to treatment. In addition, the present review evaluates its effects on sensitivity to chemotherapy, targeted therapy and radiotherapy. The current proposed strategies for the systemic delivery of miRNA‑214‑3p in cancer were also discussed.

Indexed as

Biomarkers, TumorMicroRNAsNeoplasmsApoptosisCell ProliferationGene Expression Regulation, NeoplasticHumansPrognosisBiomarkers, TumorMicroRNAsbiomarkercancer; diagnosismicroRNA‑214‑3pprognosis

Identifiers

PMID40747717
PMCPMC12340666

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.