ArticleIranian journal of parasitology
Evaluating the Effects of Imiquimod on Paths of TLRs and Inflammatory Cytokines Signaling in Infected Macrophages with
Article in Iranian journal of parasitology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Methods: This study was carried out in the Department of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, in 2018. The effect of imiquimod was investigated on non-infected and infected macrophages with Results: The expression of TLR2 decreased in non-infected macrophages were affected by the imiquimod. The expression level of TLR7 in healthy macrophages, decreased and the difference with control group was significant. Imiquimod increases the expression of inflammatory cytokines and IL12 in mouse macrophages and also decrease the expression of IL10. Conclusion: This suggests that imiquimod may improve the therapeutic effects in infected mice with
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