Evidence map›Paper›PMID 40747491›Full record

ArticleThe American statistician2025

Flexible Distributed Lag Models for Count Data Using mgcv.

Theo Economou, Daphne Parliari, Aurelio Tobias, Laura Dawkins, Hamish Steptoe, Christophe Sarran, Oliver Stoner, Rachel Lowe, Jos Lelieveld

Abstract read
In one paragraph

Article in The American statistician, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Theo EconomouDepartment of Mathematics and Statistics, University of Exeter, Exeter, UK.
Daphne ParliariLaboratory of Atmospheric Physics, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Aurelio TobiasInstitute for Environmental Assessment and Water Research, Spanish National Research Council, Barcelona, Spain.
Laura DawkinsMet Office, Exeter, UK.
Hamish SteptoeMet Office, Exeter, UK.
Christophe SarranMet Office, Exeter, UK.
Oliver StonerSchool of Mathematics and Statistics, University of Glasgow, Glasgow, UK.
Rachel LoweBarcelona Supercomputing Center (BSC), Barcelona, Spain.
Jos LelieveldClimate and Atmosphere Research, The Cyprus Institute, Nicosia, Cyprus.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this tutorial we present the use of R package mgcv to implement Distributed Lag Non-Linear Models (DLNMs) in a flexible way. Interpretation of smoothing splines as random quantities enables approximate Bayesian inference, which in turn allows uncertainty quantification and comprehensive model checking. We illustrate various modeling situations using open-access epidemiological data in conjunction with simulation experiments. We demonstrate the inclusion of temporal structures and the use of mixture distributions to allow for extreme outliers. Moreover, we demonstrate interactions of the temporal lagged structures with other covariates with different lagged periods for different covariates. Spatial structures are also demonstrated, including smooth spatial variability and Markov random fields, in addition to hierarchical formulations to allow for non-structured dependency. Posterior predictive simulation is used to ensure models verify well against the data.

Indexed as

Bayesian inferenceDLNMEnvironmental epidemiologyHeat-stressPenalized splines

Identifiers

PMID40747491
PMCPMC12312768

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.