Evidence map›Paper›PMID 40747479›Full record

ReviewArab journal of urology2025

Male accessory gland infection (MAGI): Over-diagnosed or under treated in infertile men?

Sulagna Dutta, Fahmi Bahar, Aldo E Calogero, Rupin Shah, Ashok Agarwal

Abstract readReview
In one paragraph

Review in Arab journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sulagna DuttaBasic Medical Sciences Department, College of Medicine, Ajman University, Ajman, UAE.ORCID https://orcid.org/0000-0002-7893-5282
Fahmi BaharGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-7027-9436
Aldo E CalogeroGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0001-6950-335X
Rupin ShahGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0002-7868-5949
Ashok AgarwalGlobal Andrology Forum, Moreland Hills, OH, USA.ORCID https://orcid.org/0000-0003-0585-1026

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Male accessory gland infection (MAGI) is a significant yet often under-recognized contributor to male infertility. This review article provides a comprehensive synopsis of MAGI, distinguishing it from male genital tract infection (MGTI) and emphasizing the challenges posed by asymptomatic cases. It concisely presents the pathophysiology of MAGI, highlighting the inflammatory response characterized by leukocyte infiltration, elevated pro-inflammatory cytokines, and increased production of reactive oxygen species, which collectively impair sperm quality and fertilizing capability. The article discusses the complexities in diagnosis due to the overlap with benign conditions and presents emerging diagnostic markers. It also critically reviews the controversies surrounding the over-diagnosis and under-treatment of MAGI, emphasizing the need for improved diagnostic accuracy to encourage appropriate treatment. Current therapeutic strategies are explored, revealing variable efficacy and the importance of personalized approaches. This review aims to provide a clear understanding of the clinical implications of MAGI and to guide accurate diagnosis and effective treatment, ensuring better fertility outcomes for affected patients.

Indexed as

Antibiotic therapyleukocytospermiamale accessory gland infection/inflammation (MAGI)male genital tract infection (MGTI)male infertility

Identifiers

PMID40747479
PMCPMC12308868

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.