Evidence map›Paper›PMID 40747470›Full record

ReviewArab journal of urology2025

Can lifestyle changes significantly improve male fertility: A narrative review?

Kadir Bocu, Luca Boeri, Asli Metin Mahmutoglu, Paraskevi Vogiatzi

Abstract readReview
In one paragraph

Review in Arab journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kadir BocuDepartment of Urology, Niğde Ömer Halisdemir University Faculty of Medicine, Niğde, Turkey.ORCID https://orcid.org/0000-0003-4323-4037
Luca BoeriDepartment of Urology, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Asli Metin MahmutogluDepartment of Medical Biology, Faculty of Medicine, Yozgat Bozok University, Yozgat, Turkey.
Paraskevi VogiatziAndromed Health & Reproduction, Fertility & Reproductive Health Diagnostic Center, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Male infertility is increasingly recognized as a significant global health concern, with lifestyle factors being critical contributors to declining male fertility rates. This narrative review comprehensively analyzes the impact of various lifestyle choices, including diet, physical activity, substance use, stress, sleep, weight management, sexual habits, and environmental and occupational exposures on male reproductive health. The review examines the biological and ecological mechanisms through which these lifestyle factors affect spermatogenesis and sperm quality. Furthermore, it discusses potential interventions, such as dietary modifications, weight management strategies, substance cessation programs, stress reduction techniques, and workplace policy changes to improve male fertility outcomes. Emphasis is placed on the role of oxidative stress, hormonal regulation, and DNA integrity in mediating the effects of these lifestyle factors. While lifestyle modifications can significantly enhance male reproductive health, the available evidence highlights the need for more rigorous research to establish solid guidelines and interventions for mitigating male infertility.

Indexed as

diet and nutritionenvironmental exposureslifestyle factorsMale infertilityoxidative stressspermatogenesis

Identifiers

PMID40747470
PMCPMC12308861

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.