Evidence map›Paper›PMID 40747449›Full record

ArticleEuropean heart journal. Imaging methods and practice2025

Haemodynamic implications of cardiovascular magnetic resonance pulmonary capillary wedge pressure in acute myocardial infarction.

Pankaj Garg, Aradhai Bana, Gareth Matthews, Tiya Bali, Rui Li, Zia Mehmood, Liang Zhong, Rob J van der Geest, Sven Plein, John P Greenwood and 1 more

Abstract read
In one paragraph

Article in European heart journal. Imaging methods and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pankaj GargThe Bob Champion Research & Education Building, Rosalind Franklin Road, University of East Anglia, Norwich NR4 7UQ, UK.ORCID https://orcid.org/0000-0002-5483-169X
Aradhai BanaThe Bob Champion Research & Education Building, Rosalind Franklin Road, University of East Anglia, Norwich NR4 7UQ, UK.ORCID https://orcid.org/0009-0005-3984-5005
Gareth MatthewsThe Bob Champion Research & Education Building, Rosalind Franklin Road, University of East Anglia, Norwich NR4 7UQ, UK.ORCID https://orcid.org/0000-0001-8353-4806
Tiya BaliThe Bob Champion Research & Education Building, Rosalind Franklin Road, University of East Anglia, Norwich NR4 7UQ, UK.
Rui LiThe Bob Champion Research & Education Building, Rosalind Franklin Road, University of East Anglia, Norwich NR4 7UQ, UK.
Zia MehmoodThe Bob Champion Research & Education Building, Rosalind Franklin Road, University of East Anglia, Norwich NR4 7UQ, UK.
Liang ZhongSingHealth Building, Outram Road, National Heart Centre Singapore 169608, Singapore.
Rob J van der GeestDivision of Image Processing, Leiden University Medical Center, Leiden, The Netherlands.ORCID https://orcid.org/0000-0002-9084-5597
Sven PleinThe Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Woodhouse Lane, Leeds LS2 9JT, UK.ORCID https://orcid.org/0000-0002-0997-4384
John P GreenwoodThe Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Woodhouse Lane, Leeds LS2 9JT, UK.
Peter SwobodaThe Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Woodhouse Lane, Leeds LS2 9JT, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Cardiovascular magnetic resonance (CMR)-derived pulmonary capillary wedge pressure (PCWP) has demonstrated diagnostic and prognostic utility in heart failure patients. However, its clinical value in acute myocardial infarction (AMI) remains undetermined. This study investigates the relationship between CMR-derived PCWP, myocardial injury, and left ventricular (LV) remodelling in re-perfused acute ST-elevation myocardial infarction (STEMI). Methods and results: Sixty-nine patients with STEMI underwent CMR within 48 h and at 3 months. PCWP was estimated using the sex-specific equation: CMR PCWP: 5.7591 + (0.07505 × left atrial volume) [0.05289 × left ventricular mass (LVM)] - (1.9927 × sex) [female = 0; male = 1], where LAV is left atrial volume (mL) and LVM is left ventricular mass (g). LV remodelling was assessed via changes in LV end-diastolic volume (LVEDV) and ejection fraction (LVEF). Patients with high CMR PCWP (≥18 mmHg) exhibited greater myocardial scar burden (28.5% vs. 17.2%, Conclusion: CMR-derived PCWP may be a valuable biomarker in STEMI, identifying patients at risk of adverse remodelling and LV dysfunction. Its integration into clinical practice may enhance risk stratification and guide targeted therapies.

Indexed as

follow-up studiesheart atriaheart failurehumansleft ventricular dysfunctionprognosisST elevation myocardial infarction

Identifiers

PMID40747449
PMCPMC12311366

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.