Evidence map›Paper›PMID 40747448›Full record

ArticleEuropean heart journal. Imaging methods and practice2025

Real-time guidance and automated measurements using deep learning to improve echocardiographic assessment of left ventricular size and function.

Sigbjorn Sabo, Håkon Pettersen, Gunn C Bøen, Even O Jakobsen, Per K Langøy, Hans O Nilsen, David Pasdeloup, Erik Smistad, Andreas Østvik, Lasse Løvstakken and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in European heart journal. Imaging methods and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06310330 (Technology Revising Ultrasound Solutions for Tomorrow - Anticancer-treatment Cardiotoxicity Identification by Echocardiography), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06310330 narecruitingnot on this map

Technology Revising Ultrasound Solutions for Tomorrow - Anticancer-treatment Cardiotoxicity Identification by Echocardiography

TypeinterventionalSponsorNorwegian University of Science and TechnologyRan2024 to 2026Enrolled250ConditionsBreast Neoplasm Malignant PrimaryArmsComprehensive echocardiographic follow-up, Simplified echocardiographic follow-up
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. The rise of point-of-care ultrasound in cardiopulmonary diagnostics.European heart journal. Imaging methods and practice · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sigbjorn SaboDepartment of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, PO Box 8905, Trondheim 7491, Norway.ORCID https://orcid.org/0000-0001-6906-5169
Håkon PettersenDepartment of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, PO Box 8905, Trondheim 7491, Norway.ORCID https://orcid.org/0009-0000-1173-4032
Gunn C BøenClinic of Cardiology, St. Olavs Hospital, Trondheim, Norway.
Even O JakobsenDepartment of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, PO Box 8905, Trondheim 7491, Norway.
Per K LangøyClinic of Cardiology, St. Olavs Hospital, Trondheim, Norway.
Hans O NilsenClinic of Cardiology, St. Olavs Hospital, Trondheim, Norway.
David PasdeloupDepartment of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, PO Box 8905, Trondheim 7491, Norway.ORCID https://orcid.org/0000-0002-0160-1268
Erik SmistadDepartment of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, PO Box 8905, Trondheim 7491, Norway.ORCID https://orcid.org/0000-0002-7258-4709
Andreas ØstvikDepartment of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, PO Box 8905, Trondheim 7491, Norway.ORCID https://orcid.org/0000-0003-3895-2683
Lasse LøvstakkenDepartment of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, PO Box 8905, Trondheim 7491, Norway.ORCID https://orcid.org/0000-0003-2474-9588
Stian StølenClinic of Cardiology, St. Olavs Hospital, Trondheim, Norway.
Bjørnar GrenneDepartment of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, PO Box 8905, Trondheim 7491, Norway.ORCID https://orcid.org/0000-0002-2984-6865
Håvard DalenDepartment of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, PO Box 8905, Trondheim 7491, Norway.ORCID https://orcid.org/0000-0003-1192-3663
Espen HolteDepartment of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, PO Box 8905, Trondheim 7491, Norway.ORCID https://orcid.org/0000-0002-8891-1372

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: The low reproducibility of echocardiographic measurements challenges the identification of subtle changes in left ventricular (LV) function. Deep learning (DL) methods enable real-time analysis of acquisitions and may improve echocardiography. The aim of this study was to evaluate the impact of DL-based guidance and automated measurements on the reproducibility of LV global longitudinal strain (GLS), end-diastolic (EDV) and end-systolic (ESV) volume, and ejection fraction (EF). Methods and results: Forty-six patients (24 breast cancer and 22 general cardiology patients) were included and underwent four consecutive echocardiograms. Six were included twice, totalling 52 inclusions and 208 echocardiograms. One sonographer-cardiologist pair used DL guidance and measurements (DL group), while another did not use DL tools and performed manual measurements (manual group). DL group recordings were also measured using a commercially available DL-based EF tool. For GLS, the DL group had a 30% lower test-retest variability than the manual group (minimal detectable change 2.0 vs. 2.9, Conclusion: Combining real-time DL guidance with automated measurements improved the reproducibility of LV size and function measurements compared with usual care, but future studies are needed to evaluate its clinical effect. Trial registration number: NCT06310330.

Indexed as

deep learningejection fractionreproducibilitystraintest–retest

Identifiers

PMID40747448
PMCPMC12311362

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.