Evidence map›Paper›PMID 40747268›Full record

ArticleFrontiers in neuroanatomy2025

The orca (

Paula Alonso-Almorox, Alfonso Blanco, Carla Fiorito, Jose C Gómez-Villamandos, M A Risalde, Javier Almunia, Antonio Fernández

Abstract read
In one paragraph

Article in Frontiers in neuroanatomy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Paula Alonso-AlmoroxVeterinary Histology and Pathology, Atlantic Center for Cetacean Research (CAIC), Veterinary School, University Institute of Animal Health and Food Safety (IUSA), University of Las Palmas de Gran Canaria, Arucas, Spain.
Alfonso BlancoDepartment of Anatomy and Comparative Pathology and Anatomy, University of Córdoba, Córdoba, Spain.
Carla FioritoCentro para el Estudio de Sistemas Marinos CESIMAR-CONICET, Puerto Madryn, Chubut, Argentina.
Jose C Gómez-VillamandosDepartment of Anatomy and Comparative Pathology and Anatomy, University of Córdoba, Córdoba, Spain.
M A RisaldeDepartment of Anatomy and Comparative Pathology and Anatomy, University of Córdoba, Córdoba, Spain.
Javier AlmuniaLoro Parque Fundación, Puerto de la Cruz, Spain.
Antonio FernándezVeterinary Histology and Pathology, Atlantic Center for Cetacean Research (CAIC), Veterinary School, University Institute of Animal Health and Food Safety (IUSA), University of Las Palmas de Gran Canaria, Arucas, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pituitary gland is central to endocrine regulation in vertebrates, coordinating key physiological processes such as growth, reproduction, and stress responses. In cetaceans, and particularly in large odontocetes like orcas (Orcinus orca), understanding pituitary structure is essential for advancing neuroendocrine research and informing welfare and health assessments. Despite their ecological, cognitive, and conservation significance, detailed morphological studies of the orca pituitary gland remain scarce. In this study, we conducted a comprehensive structural and ultrastructural analysis of the orca pituitary gland using postmortem samples from four captive individuals. We combined computed tomography, histology, immunohistochemistry, and transmission electron microscopy to examine the gland's anatomical organization and cellular composition. Our results reveal features consistent with other cetaceans as well as species-specific characteristics, including the distribution and morphology of endocrine cells within the adenohypophysis and neurohypophysis. These findings provide the first integrated anatomical and ultrastructural reference for the orca pituitary gland, offering valuable insights into cetacean neuroendocrinology and supporting improved species-specific welfare evaluation, health monitoring, and management practices for orcas under human care.

Indexed as

cetaceanelectron microscopyhistologyimmunohistochemistryneuroendocrineneuroendocrine systemorcapituitary gland

Identifiers

PMID40747268
PMCPMC12310606

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.