Evidence map›Paper›PMID 40747236›Full record

ReviewWorld journal of hepatology2025

Liver regeneration after partial hepatectomy: Triggers and mechanisms.

Bakari Korchilava, Tamar Khachidze, Nino Megrelishvili, Lika Svanadze, Manana Kakabadze, Keti Tsomaia, Memed Jintcharadze, Dimitri Kordzaia

Abstract readReview
In one paragraph

Review in World journal of hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
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  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. 6-Antioxidants (Basel, Switzerland) · 2025
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bakari KorchilavaDepartment of Clinical Anatomy and Operative Surgery, Ivane Javakhishvili Tbilisi State University, Tbilisi 0159, Georgia.
Tamar KhachidzeDepartment of Clinical Anatomy, Tbilisi State Medical University, Tbilisi 0130, Georgia.
Nino MegrelishviliDepartment of Pathology, Ivane Javakhishvili Tbilisi State University, Tbilisi 0159, Georgia.
Lika SvanadzeAlexandre Natishvili Institute of Morphology, Ivane Javakhishvili Tbilisi State University, Tbilisi 0159, Georgia.
Manana KakabadzeAlexandre Natishvili Institute of Morphology, Ivane Javakhishvili Tbilisi State University, Tbilisi 0159, Georgia.
Keti TsomaiaAlexandre Natishvili Institute of Morphology, Ivane Javakhishvili Tbilisi State University, Tbilisi 0159, Georgia.
Memed JintcharadzeDepartment of Oncosurgery, Batumi High-Tech Hospital, Medical Center, Batumi 6000, Ajaria, Georgia.
Dimitri KordzaiaAlexandre Natishvili Institute of Morphology, Ivane Javakhishvili Tbilisi State University, Tbilisi 0159, Georgia. dimitri.kordzaia@tsu.ge.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver regeneration (LR) following partial hepatectomy (PH) is a unique and complex physiological response that restores hepatic mass and function through tightly orchestrated cellular and molecular events. Traditionally viewed as a proliferation-driven process, LR is now understood to involve both hepatocyte hyperplasia and hypertrophy, triggered primarily by hemodynamic alterations such as increased portal pressure and shear stress. These promote LR through endothelial-hepatocyte communication

Indexed as

Cytokines and growth factorsDuctular reactionLiver regenerationMolecular pathwaysPartial hepatectomyPortal flowPortal pressureStructural remodeling

Identifiers

PMID40747236
PMCPMC12308566

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.