ArticleCureus2025
Successful Conservative Management of Aplasia Cutis Congenita in a Preterm Neonate.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Aplasia cutis congenita with fetus papyraceus (Frieden classification Type V)-systematic review of literature and reported cases from 1990 to 2025 with a proposed revised diagnostic criteria and management algorithm.European journal of pediatrics · 2026Pooled it
- Adams-Oliver Syndrome: A Comprehensive Literature Review of Clinical, Nutritional, Genetic, and Molecular Aspects with Nursing Care Considerations.International journal of molecular sciences · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aplasia cutis congenita (ACC), type 5, is considered a rare condition and is typically recognized by symmetric skin defects visible at birth. Due to the limited number of documented cases, there are no established management guidelines, which can result in the use of unnecessary surgical or antibiotic interventions that may expose newborns to avoidable risks. We present a case from Gagua Clinic in Tbilisi, Georgia, involving a newborn with large, symmetric lesions on the trunk and around the umbilicus, which were managed conservatively and showed complete re-epithelialization over the course of a few months. This case highlights the successful conservative management of ACC with extensive skin defects, achieved without the need for surgery or antibiotics.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.