Evidence map›Paper›PMID 40747175›Full record

ArticleCureus2025

Hemophagocytic Lymphohistiocytosis and the Liver Masquerade.

Hadasa Banayan, Jieqi Liu, Dominique Haoson

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hadasa BanayanInternal Medicine, Jersey City Medical Center/RWJ Barnabas Health, Jersey City, USA.
Jieqi LiuHematology and Oncology, Division of Blood Disorders, Rutgers Cancer Institute of New Jersey, New Brunswick, USA.
Dominique HaosonInternal Medicine, Jersey City Medical Center/RWJ Barnabas Health, Jersey City, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a case of hemophagocytic lymphohistiocytosis (HLH) with a complex presentation that could have been easily mistaken as one of many alternative diagnoses. Our patient, with chronic alcohol use disorder, presented with new-onset liver symptoms and pancytopenia. This case underscores the importance of clinical suspicion and further investigation of a wide differential. The purpose of this case report is to highlight the diagnostic challenges and nuances in patient presentation that can mislead healthcare providers while emphasizing the ambiguity of liver failure symptoms in patients with undiagnosed HLH.

Indexed as

acute alcoholic hepatitisacute liver failure (alf)acute-on-chronic liver failurealcoholic liver failurechronic liver disease (cld)diffuse large b cell lymphoma (dlbcl)hemophagocytic lymphohistiocytosis (hlh)hereditary hemochromatosis (hh)hyperferritinemiapancytopenia

Identifiers

PMID40747175
PMCPMC12313311

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.