Evidence map›Paper›PMID 40747123›Full record

ArticleBladder (San Francisco, Calif.)2025

Expression profiles and clinical significance of cystatin family genes in transitional cell carcinoma of the urinary bladder.

Haixia Xu, Wang Liu, Xiangxing Kuang, Jiang Zhao, Xiangwei Wang, Benyi Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bladder (San Francisco, Calif.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Haixia XuDepartment of Medical Oncology, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, Guandong 518035, China.
Wang LiuDepartment of Urology, School of Medicine, The University of Kansas Medical Center, Kansas 66160, United States of America.
Xiangxing KuangDepartment of Urology, Guangzhou Hospital of Integrated Traditional and Western Medicine, Guangzhou, Guangdong 510803, China.
Jiang ZhaoDepartment of Urology, School of Medicine, Guangdong Medical University, Zhanjiang, Guangdong 524001, China.
Xiangwei WangDepartment of Urology, School of Medicine, Guangdong Medical University, Zhanjiang, Guangdong 524001, China.
Benyi LiDepartment of Urology, School of Medicine, The University of Kansas Medical Center, Kansas 66160, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cystatins, encoded by the Objective: This study examined the expression profiles of the cystatin family genes and analyzed their correlation with clinicopathological parameters using the Cancer Genome Atlas Bladder Cancer RNA-seq dataset. Methods: The RNAseq dataset derived from the Cancer Genome Atlas project was utilized for the gene expression analysis on the XIANTAO online platform. The UALCAN online platform was used for the analysis of gene expression in molecular subgroups. The differences among various subgroups were statistically analyzed to define the significance. Results: Our results showed that Conclusion:

Indexed as

Bladder cancerCystatin family genesDisease progressionDNA methylationImmune infiltrationSurvival outcomes

Identifiers

PMID40747123
PMCPMC12308117

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.