Evidence map›Paper›PMID 40746980›Full record

ArticleSurgical case reports2025

Successful Use of Extracorporeal LVAD for Cardiogenic Shock with Aortic Valve Regurgitation as Bridge to Surgery.

Takura Taguchi, Takuji Kawamura, Daisuke Yoshioka, Shunsuke Saito, Ai Kawamura, Yusuke Misumi, Shigeru Miyagawa

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In one paragraph

Article in Surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Takura TaguchiDepartment of Cardiovascular Surgery, University of Osaka Graduate School of Medicine, Suita, Osaka, Japan.
Takuji KawamuraDepartment of Cardiovascular Surgery, University of Osaka Graduate School of Medicine, Suita, Osaka, Japan.
Daisuke YoshiokaDepartment of Cardiovascular Surgery, University of Osaka Graduate School of Medicine, Suita, Osaka, Japan.
Shunsuke SaitoDepartment of Cardiovascular Surgery, University of Osaka Graduate School of Medicine, Suita, Osaka, Japan.
Ai KawamuraDepartment of Cardiovascular Surgery, University of Osaka Graduate School of Medicine, Suita, Osaka, Japan.
Yusuke MisumiDepartment of Cardiovascular Surgery, University of Osaka Graduate School of Medicine, Suita, Osaka, Japan.
Shigeru MiyagawaDepartment of Cardiovascular Surgery, University of Osaka Graduate School of Medicine, Suita, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIntra-aortic balloon pumping (IABP), Impella, and veno-arterial extracorporeal membrane oxygenation (VA-ECMO) are common percutaneous devices used to manage hemodynamic instability in patients with cardiogenic shock. These devices play a critical role in providing circulatory support. However, they may fail to achieve sufficient left ventricular unloading in patients with aortic valve regurgitation (AR), potentially complicating treatment strategies. In such challenging cases, an extracorporeal left ventricular assist device (LVAD) may serve as an effective alternative solution. CASE PRESENTATION: A 61-year-old man presented with heart failure and cardiogenic shock, further complicated by AR. Despite intensive inotropic therapy, his condition deteriorated, leading to significant hepatic and renal dysfunction. Echocardiography revealed left ventricular dysfunction with an ejection fraction of 23.5%, as well as moderate aortic, mitral, and tricuspid valve regurgitation. Initial management with VA-ECMO proved inadequate, necessitating the implantation of an extracorporeal LVAD. This intervention resulted in marked improvements in hemodynamics and multi-organ function. Subsequently, the patient underwent successful surgical procedures, including aortic valve replacement, mitral and tricuspid annuloplasty, and pulmonary vein isolation. He was discharged on day 51.

conclusionsThis case highlights the challenges in managing cardiogenic shock with AR, where conventional devices like IABP, Impella, and VA-ECMO may exacerbate the condition. The use of an extracorporeal LVAD provided effective left ventricular unloading, enabling successful preoperative optimization and surgery. This case supports the utility of LVAD as a bridge to surgery in patients with cardiogenic shock and AR, suggesting a need for further research into optimal management strategies in such complex cases.

Indexed as

aortic valve regurgitationcardiogenic shockcase reportextracorporeal left ventricular assist device

Identifiers

PMID40746980
PMCPMC12310382

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