Evidence map›Paper›PMID 40746819›Full record

ArticleCureus2025

Left Ventricular Noncompaction Cardiomyopathy in an Elderly Patient: A Case Report.

Reza Alavi, Hector Armando Sanchez Garcia, Mohamad Ahmad, Rami Akel

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Reza AlaviInternal Medicine, Hospital Corporation of America (HCA) Florida Bayonet Point Hospital, Hudson, USA.
Hector Armando Sanchez GarciaInternal Medicine, Hospital Corporation of America (HCA) Florida Bayonet Point Hospital, Hudson, USA.
Mohamad AhmadCardiology, Hospital Corporation of America (HCA) Florida Bayonet Point Hospital, Hudson, USA.
Rami AkelInterventional Cardiology, Hospital Corporation of America (HCA) Florida Bayonet Point Hospital, Hudson, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Left ventricular noncompaction is a rare cardiomyopathy, often underrecognized in older adults, characterized by prominent myocardial trabeculations and deep intertrabecular recesses. These structural abnormalities can lead to heart failure, arrhythmias, and thromboembolic events. We report the case of an 85-year-old woman with a history of heart failure with preserved ejection fraction and atrial fibrillation who presented with chest pain and dyspnea. Her electrocardiogram (ECG) revealed new diffuse T-wave inversions. Coronary angiography showed no obstructive disease. Transthoracic echocardiography demonstrated features consistent with left ventricular noncompaction cardiomyopathy (LVNC), including a noncompacted-to-compacted ratio greater than 2:1, along with a reduced left ventricular ejection fraction (LVEF) of 25-30% (normal LVEF >55%). Cardiac MRI was recommended to further characterize the myocardial structure, but the patient declined. She was managed with guideline-directed medical therapy for heart failure and anticoagulation and discharged with a wearable defibrillator. While LVNC is congenital, it may remain undiagnosed until later in life, particularly when symptoms arise due to progressive systolic dysfunction. This case illustrates the delayed diagnosis of a congenital condition rather than a late-onset disease. Greater awareness of LVNC and use of advanced imaging modalities, such as cardiac MRI, are important to improve recognition and management in older adults.

Indexed as

cardiomyopathyechocardiographyleft ventricular noncompaction cardiomyopathynoncompacted-to-compacted ratiostructural heart diseasetrabeculations

Identifiers

PMID40746819
PMCPMC12310411

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.