Evidence map›Paper›PMID 40746769›Full record

ArticleClinical case reports2025

Myelodysplastic Syndrome in a Patient With Cronkhite-Canada Syndrome.

Kevin G Shim, Kevork Khadarian, Jewel Samadder, Jiehao Zhou, Cecilia Arana Yi

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kevin G ShimDepartment of Medicine Mayo Clinic, Hematology and Medical Oncology Phoenix Arizona USA.ORCID https://orcid.org/0000-0002-3448-9452
Kevork KhadarianDepartment of Gastroenterology and Hepatology Mayo Clinic Scottsdale Arizona USA.
Jewel SamadderDepartment of Gastroenterology and Hepatology Mayo Clinic, Center of Individualized Medicine Scottsdale Arizona USA.
Jiehao ZhouDepartment of Laboratory Medicine and Pathology Mayo Clinic Phoenix Arizona USA.
Cecilia Arana YiDepartment of Medicine Mayo Clinic, Hematology and Medical Oncology Phoenix Arizona USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cronkhite-Canada Syndrome (CCS) is a rare non-hereditary gastroenterological polyposis syndrome without a clear etiology. Myelodysplastic syndromes (MDS) are clonal hematological disorders. Immune dysregulation has been posited as a contributor to the development of both. A 70-year-old man developed chronic diarrhea, dysgeusia, and onycholysis. Endoscopic evaluation and testing to exclude hereditary polyposis syndromes resulted in a diagnosis of CCS. Approximately 1 year later, he was noted to have persistent anemia, which was ultimately diagnosed as MDS. He was evaluated with a myeloid disorder next-generation sequencing panel and found to have mutations in

Indexed as

clonal hematopoiesisCronkhite‐Canada Syndromelow‐risk myelodysplastic syndromesmyelodysplastic syndromesmyelodysplastic syndrome with single‐lineage dysplasia

Identifiers

PMID40746769
PMCPMC12311222

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.