ArticleFrontiers in neurology2025
The effect of rTMS intervention with different targets on neural remodeling in stroke patients: a randomized controlled trial.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- TMS-Derived Neurophysiological Measures of Corticospinal Excitability, Intracortical Excitability, and Interhemispheric Interactions Associated With Post-Stroke Motor Recovery: A Systematic Review.The European journal of neuroscience · 2026Pooled it
- Deep and repetitive transcranial magnetic stimulation improves motor dysfunction after basal ganglia infarction: preliminary findings on efficacy and electrophysiological mechanisms.Frontiers in neuroscience · 2026Article
- Comparative efficacy and mechanistic insights of non-invasive neuromodulation and motor rehabilitation on functional reorganization of the supplementary motor area in subacute stroke: a narrative review.Frontiers in physiology · 2026Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: rTMS is widely used to improve motor function in patients with ischemic stroke, but there are few studies on different targets. In order to develop a clinical precision rehabilitation program, this study aims to explore the effects of rTMS at different targets on neural remodeling in patients with subcortical stroke by combining motor function assessment, multimodal MRI and electrophysiological methods. Methods: 69 stroke patients were randomly assigned to the sham group, M1 group, and SMA group. Functional assessment was performed using the exercise and balance scale, and rsfMRI, DTI, VBM, and MEP were used to evaluate the changes in rsFC, white matter tracts, gray matter volume, and neurophysiology before and after intervention. Results: Following the intervention, the SMA group demonstrated significantly greater improvement in motor function compared to the M1 group ( Conclusion: High-frequency SMA-TMS intervention on the affected side has a better improvement than traditional M1 target in stroke with motor function. We provide neuroimaging and neurophysiological evidence for different target rTMS interventions in motor related networks after stroke. Clinical trial registration: www.chictr.org.cn, identifier ChiCTR2200060955.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.