Evidence map›Paper›PMID 40746638›Full record

ArticleRespirology case reports2025

Management of Primary Ciliary Dyskinesia in a Kartagener's Syndrome Patient With Total Situs Inversus.

Ivan H Huang, Kenneth N Dang, Saarang Kashyap, Alexander J Sweidan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Respirology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ivan H HuangDepartment of Physiological Science University of California Los Angeles California USA.ORCID https://orcid.org/0009-0009-1114-6754
Kenneth N DangDepartment of Neuroscience University of California Los Angeles California USA.ORCID https://orcid.org/0009-0001-7207-5699
Saarang KashyapDepartment of Microbiology, Immunology & Molecular Genetics University of California Los Angeles California USA.
Alexander J SweidanDepartment of Pulmonary/Critical Care Medicine, Irvine School of Medicine University of California Los Angeles California USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kartagener's syndrome is a rare, autosomal recessive disorder characterised by primary ciliary dyskinesia (PCD) resulting in impaired mucociliary clearance and situs inversus. Common symptoms are chronic recurrent rhinosinusitis, bronchiectasis, otitis media and pneumonia. We report the case of a 62-year-old female patient with complete situs inversus of the chest and abdominal organs. Bronchoscopic washout of the lungs was performed for therapeutic benefit and culturing for targeted antibacterial therapy. Patients affected by Kartagener's syndrome are vulnerable to repeated respiratory infections and lower BMI due to impaired mucociliary clearance from PCD. Multimodal airway clearance through pulmonary hygiene is a research-backed strategy in treating this condition. This case highlights the importance of a comprehensive and effective management approach for patients with symptomatic Kartagener's syndrome and other forms of primary ciliary dyskinesia (PCD).

Indexed as

chronic inflammationKartagener's syndromemucociliary clearanceMycobacterium abscessusotitis mediapneumoniaPseudomonas aeruginosaunderweight

Identifiers

PMID40746638
PMCPMC12310814

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.