Evidence map›Paper›PMID 40746633›Full record

ArticleLaryngoscope investigative otolaryngology2025

Ongoing Discrepancy Between Unilateral Meniere's Disease and Bilateral Endolymphatic Hydrops on Hydrops MRI.

Ting-Hua Yang, Ling-Chen Meng, Yi-Ho Young

Abstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ting-Hua YangDepartment of Otolaryngology National Taiwan University Hospital Taipei Taiwan.
Ling-Chen MengDepartment of Otolaryngology National Taiwan University Hospital Taipei Taiwan.
Yi-Ho YoungDepartment of Otolaryngology Far Eastern Memorial Hospital New Taipei Taiwan.ORCID https://orcid.org/0000-0002-3194-5811

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: In the era of Hydrops MRI, a clinical dilemma has emerged: while Meniere's disease (MD) is diagnosed unilaterally, Hydrops MRI demonstrates endolymphatic hydrops (EH) bilaterally. This study aims to clarify this ongoing discrepancy. Methods: Fifty-six MD patients underwent an inner ear test battery followed by 3 T Hydrops MRI. Eight unilateral MD patients with EH on both ears were classified as Group A and subdivided into Groups A1 (symptomatic EH on the affected ear, Results: Both Groups A1 and B1 showed a significantly declining sequence of abnormality rates running from audiometry, cervical, and ocular vestibular-evoked myogenic potential tests to caloric test. However, such a declining trend was not observed in Groups A2 and B2. Significant differences in the abnormality rates of audiometry were noted in Groups A1 (88%) versus A2 (0) and Groups B1 (94%) versus B2 (27%). Four (50%) out of eight ears in Group A2 progressed to MD after a mean interval of 4 ± 2 years. Conclusion: If Hydrops MRI identifies EH in both ears of a unilateral MD patient, monitoring cochlear symptoms, hearing thresholds, and imaging findings in the opposite (unaffected) ear may help predict the progression from unilateral MD to bilateral MD. Level of Evidence: 4.

Indexed as

asymptomatic hydropsendolymphatic hydropshydrops MRIinner ear test batteryMeniere's disease

Identifiers

PMID40746633
PMCPMC12311983

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.