Evidence map›Paper›PMID 40746610›Full record

ArticleFrontiers in oncology2025

Percutaneous transhepatic recanalization of occluded prosthetic graft after pancreatoduodenectomy with venous reconstruction for pancreatic cancer.

Nils Degrauwe, Didier Roulin, Vincent Dunet, Nermin Halkic, Nicolas Demartines, Antonia Digklia, Nicolas Villard, Alban Denys, Georgia Tsoumakidou, Rafael Duran

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In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nils DegrauweDepartment of Radiology and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Didier RoulinDepartment of Visceral Surgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Vincent DunetDepartment of Radiology and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Nermin HalkicDepartment of Visceral Surgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Nicolas DemartinesDepartment of Visceral Surgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Antonia DigkliaDepartment of Oncology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Nicolas VillardDepartment of Radiology and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Alban DenysDepartment of Radiology and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Georgia TsoumakidouDepartment of Radiology and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Rafael DuranDepartment of Radiology and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: To investigate the feasibility, safety, and efficacy of percutaneous transhepatic endovascular recanalization and stenting after venous graft thrombosis in pancreatic cancer patients who underwent pancreatoduodenectomy (PD) with venous reconstruction and assess risk factors of occlusion. Methods: This retrospective study was approved by the institutional review board. The clinical characteristics of 227 patients who underwent PD were compared among patients who underwent PD with/without porto-mesenteric venous resection (PMVR) ± prosthetic graft interposition. Results: Out of 227 patients, 18 (8%) underwent PD with PMVR and prosthetic graft interposition. Seven out of 18 patients had prosthetic graft occlusion. Occlusion was symptomatic in most cases (86%) and associated with tumor recurrence in 43%. On univariable logistic regression analysis, small postoperative graft diameter (OR: 0.141; 95% CI 0.021-0.970) and caudal anastomosis diameter measured on CT (OR: 0.226; 95% CI 0.059-0.859) were clear predictors of graft occlusion ( Discussion: Percutaneous transhepatic prosthetic graft recanalization and stenting is feasible and may be considered a safe and effective technique with immediate restoration of porto-mesenteric blood flow and symptom relief. Small grafts and venous anastomosis diameters are particularly at risk of thrombosis.

Indexed as

pancreatic cancerpancreatoduodenectomyrecanalizationsurvivalvenous graft thrombosisvenous resection

Identifiers

PMID40746610
PMCPMC12310483

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