ArticleFrontiers in immunology2025
Multiple analytical perspectives of mitochondrial genes in the context of preeclampsia: potential diagnostic markers.
Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Aberrant Uteroplacental and Vascular Signaling and Remodeling by Matrix Metalloproteinases in Pregnancy-Related Hypertension and Preeclampsia.Biomolecules · 2026Review
- Identifying mitochondrial genes and potential biological functions in pre-eclampsia: bioinformatics and experimental insights.Frontiers in genetics · 2026Article
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7 authors.
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Abstract
Preeclampsia(PE) is closely linked to adverse maternal and fetal outcomes. Given the pivotal roles of mitochondria in various human diseases and the limited research on their involvement in PE, this study identified biomarkers linked to mitochondrial metabolism in PE and their roles in its pathogenesis. Data from three datasets were integrated using the ComBat algorithm to mitigate batch effects. Differential expression analysis identified genes differentially expressed between PE cases and Control group. Cross-referencing these genes with mitochondrial energy metabolism-related genes (MMRGs) isolated mitochondrial energy metabolism-related differentially expressed genes (MMRDEGs). GO and KEGG analysis were performed to elucidate the functions of the MMRDEGs. A diagnostic model using Random Forest and logistic regression was validated by ROC curve analysis. mRNA expressions of
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