Evidence map›Paper›PMID 40746514›Full record

ArticleWorld journal of radiology2025

Spinal cord ischemia: The "snake bite sign".

Nikolaos-Achilleas Arkoudis, Anastasia Karachaliou, George Triantafyllou, Andreas Papadopoulos, Christos Koutserimpas, Georgios Velonakis

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Article in World journal of radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Nikolaos-Achilleas ArkoudisDepartment of Radiology 2, General University Hospital "Attikon", National and Kapodistrian University of Athens, Chaidari 12462, Attikí, Greece.
Anastasia KarachaliouDepartment of Radiology 2, General University Hospital "Attikon", National and Kapodistrian University of Athens, Chaidari 12462, Attikí, Greece.
George TriantafyllouDepartment of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, Goudi 11527, Greece.
Andreas PapadopoulosDepartment of Radiology 2, General University Hospital "Attikon", National and Kapodistrian University of Athens, Chaidari 12462, Attikí, Greece.
Christos KoutserimpasSchool of Rehabilitation Health Sciences, University of Patras, Patra 26504, Dytikí Elláda, Greece.
Georgios VelonakisDepartment of Radiology 2, General University Hospital "Attikon", National and Kapodistrian University of Athens, Chaidari 12462, Attikí, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Descriptive signs in radiology can aid in easier pattern recognition and quicker diagnosis. In spinal cord ischemia, paired anterior-horn T2-hyperintensities have traditionally been known as the "owl's eyes" or "snake eyes" sign. We discuss how these signs, while visually apt, convey no pathophysiologic context and propose renaming this finding the "snake bite sign". The image still evokes two punctate marks, yet the metaphor extends to a snake bite (two fang-like dots) rather than two bright foci (eyes) staring back at the viewer. Moreover, besides the sign metaphorically resembling a traumatic puncture of the two fangs, on the occasion of a venomous snake bite occurring elsewhere, additional neurological consequences may occur, paralleling the neurological deficits seen in anterior spinal artery infarction and several mimicking myelopathies, thus further highlighting the analogy. Such clinically driven terminology may facilitate teaching, enable diagnostic recall, and improve interdisciplinary communication.

Indexed as

BiteCordEyesIschemiaNeuroimagingNeuroradiologyOwlRadiologySnakeSpinal

Identifiers

PMID40746514
PMCPMC12308545

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.