ArticleJournal of conservative dentistry and endodontics2025
Effect of radiation on microhardness and ultramorphological changes in dentin - An
Article in Journal of conservative dentistry and endodontics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Direct radiation damage to human tooth under IMRT for head and neck cancer: physicochemical evidence supporting a non-salivary mechanism for radiation-related caries.Radiation and environmental biophysics · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Radiation therapy, which is frequently used to treat head-and-neck cancers, significantly alters the characteristics of dentin, making it more vulnerable to radiation caries. Aim and Objectives: To analyse the effect of radiation on microhardness and morphology of dentin. Materials and Methodology: After obtaining the Institutional ethical clearance (Nu/CEC/BRNS-01/2015), 40 freshly extracted molar teeth were obtained from the Department of Oral and Maxillofacial Surgery at the A. B. Shetty Memorial Institute of Dental Sciences, Mangalore. The teeth were disinfected and cleaned as per Occupational Safety and Health Administration regulations. The tooth samples were stored in distilled water at 4°C-8°C for further use. The roots of the tooth were removed and bisected longitudinally in mesiodistal direction using carborundum disc and a micromotor. The dentin's microhardness and Scanning Electron Microscopy (SEM) were examined before and after radiation. Result: Following radiation, the microhardness of the superficial, intermediate, and deep dentin significantly decreased ( Conclusion: The radiation treatment decreases the microhardness of the dentin. 70 Gy radiation is damaging to dental tissues and can cause radiation caries. Damage to collagen fibrils causes changes in dentin, which significantly lowers the hardness and stability of dentin and lowers the microhardness of superficial, intermediate, and deep dentin. The SEM analysis showed the total destruction of tubule morphology postradiation.
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