Evidence map›Paper›PMID 40746344›Full record

ArticleJHLT open2025

Increased arterial stiffness and heart rate variability over time in heart transplant recipients: A cross-sectional study using peripheral arterial tonometry.

Juliana Andrade Ferreira de Souza, Daniella Cunha Brandão, Maria da Glória Rodrigues-Machado, Bruna T S Araújo, Caio Morais, Alice Miranda Dos Santos, Antônio Christian Evangelista Gonçalves, Maria Inês Remígio de Aguiar, Shirley Lima Campos, Armèle Dornelas de Andrade

Abstract read
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Article in JHLT open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Juliana Andrade Ferreira de SouzaPhysiotherapy Department Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil.
Daniella Cunha BrandãoPhysiotherapy Department Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil.
Maria da Glória Rodrigues-MachadoPost-Graduate Program in Health Sciences of Medical Sciences, Faculty of Minas Gerais (FMC-MG), Belo Horizonte, Minas Gerais, Brazil.
Bruna T S AraújoPhysiotherapy Department Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil.
Caio MoraisPhysiotherapy Department Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil.
Alice Miranda Dos SantosPhysiotherapy Department Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil.
Antônio Christian Evangelista GonçalvesDepartment of Anesthesiology, Real Hospital Português de Pernambuco, Recife, Pernambuco, Brazil.
Maria Inês Remígio de AguiarDepartment of Semiology, Clinical Hospital, Federal University of Pernambuco, Recife, Pernambuco, Brazil.
Shirley Lima CamposPhysiotherapy Department Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil.
Armèle Dornelas de AndradePhysiotherapy Department Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Arterial stiffness represented by Augmentation index (AIx) and heart rate variability (HRV) are established predictors of cardiovascular risk in heart transplant (HTx) recipients. However, the relationship between AIx and HRV in this population remains insufficiently explored, and factors such as time after transplantation may influence both metrics. Objective: The purpose of this study was to evaluate vascular function through Aix and HRV parameters in HTx patients, both assessed by peripheral arterial tonometry (PAT). Methods: A cross-sectional study was conducted with 35 adults aged 18 to 65 years, HTx ≥ 6 months after surgery, with stable clinical condition and no changes over the last 3 months of immunosuppressive treatment. AIx and HRV were assessed using PAT. Results: Participants were categorized into 2 groups based on AIx values: high AIx ( Conclusions: Arterial stiffness assessed by PAT was higher in patients with a longer time after heart transplantation. Similarly, HRV indices, which reflect several cardiovascular health conditions, such as SDNN and sympathovagal balance (LF/HF ratio) were higher in the group with higher arterial stiffness in individuals after heart transplantation.

Indexed as

arterial stiffnessaugmentation indexendothelial functionheart rate variabilityheart transplant

Identifiers

PMID40746344
PMCPMC12310395

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.