ArticleOrganic & biomolecular chemistry2025
DNA base pairs: the effect of the aromatic ring on the strength of the Watson-Crick hydrogen bonding.
Article in Organic & biomolecular chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
- A Novel Label-Free Fluorescent Turn-on Method for the Determination of Guanine Using Levodopa.Journal of fluorescence · 2026Article
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8 authors.
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Abstract
The aromatic ring in DNA bases affects the Watson-Crick binding strength. Our quantum-chemical analyses, which compare the hydrogen bonding between the DNA bases and unsaturated analogs lacking the aromatic ring, reveal that this arises not from π-resonance assistance but from the electron-withdrawing (purines) or electron-donating (pyrimidines) effect of the heteroatom-containing ring on the frontier atoms. This electron redistribution modulates the electrostatics, steric Pauli repulsion, and σ-orbital interactions upon hydrogen bonding.
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