Evidence map›Paper›PMID 40746141›Full record

ArticleClinical endoscopy2025

Double-balloon is equal to motorized spiral enteroscopy in a German prospective, randomized trial.

Mate Knabe, Myriam Heilani, Jens Wetzka, Lukas Welsch, Georg Dultz, Insa Aschmoneit-Messer, Eva Herrmann, Stefan Zeuzem, Andrea May

Abstract read
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In one paragraph

Article in Clinical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mate KnabeCenter Gastroenterology Bethanien Bethanien Hospital Frankfurt, Frankfurt, Germany.
Myriam HeilaniDepartment of Internal Medicine I, Hospital of the Goethe University Frankfurt, Frankfurt, Germany.
Jens WetzkaDepartment of Gastroenterology, Oncology and Pneumology, Asklepios Paulinen Klinik, Wiesbaden, Germany.
Lukas WelschDepartment of Internal Medicine II, Klinikum Hanau, Hanau, Germany.
Georg DultzDepartment of Internal Medicine I, Hospital of the Goethe University Frankfurt, Frankfurt, Germany.
Insa Aschmoneit-MesserDepartment of Gastroenterology, Oncology and Pneumology, Asklepios Paulinen Klinik, Wiesbaden, Germany.
Eva HerrmannDepartment of Medicine, Institute of Biostatistics and Mathematical Modeling, Goethe University of Frankfurt, Frankfurt, Germany.
Stefan ZeuzemDepartment of Internal Medicine I, Hospital of the Goethe University Frankfurt, Frankfurt, Germany.
Andrea MayDepartment of Gastroenterology, Oncology and Pneumology, Asklepios Paulinen Klinik, Wiesbaden, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDeep enteroscopy is a challenging and time-consuming procedure. Two devices have become the clinical standards for patients: double-balloon enteroscopy (DBE) and motorized spiral enteroscopy (mSPE). Initially, mSPE demonstrated impressive results, with high rates of total enteroscopy, which were superior to those of all other devices. However, for safety reasons, mSPE was withdrawn from the market, and it remains uncertain whether it will return after technical improvements. This prospective randomized trial aimed to compare the DBE and mSPE.

methodsPatients indicated for enteroscopy were randomized to undergo either mSPE or DBE. The time to diagnosis or complete enteroscopy was measured, and all complications were recorded.

resultsA total of 48 enteroscopic procedures were performed, including 23 mSPE and 25 DBE. No significant difference was noted in the procedure time (p=0.212). The mSPE group exhibited a shorter mean procedure time of 54 (range, 15-114; standard deviation [SD], 26) minutes, whereas the DBE group had a mean procedure time of 63 (range, 20-131; SD, 25) minutes. One perforation was seen in the mSPE group.

conclusionsDBE and mSPE are both effective enteroscopy methods but showed no significant difference in this randomized trial (German trial registry: DRKS 00025890).

Indexed as

Double-balloon enteroscopyMotorized spiral enteroscopySmall bowel disorders

Identifiers

PMID40746141
PMCPMC12314608

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.