Evidence map›Paper›PMID 40746119›Full record

ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2025

The Persistent Poverty Initiative's Framework to Address Social and Economic Determinants of Cancer.

Robert A Hiatt, Amy E Kennedy, Alexandra K Adams, Karen M Basen-Engquist, Melissa L Bondy, Luis G Carvajal-Carmona, Mona Fouad, David B Grusky, Phoenix Matthews, Lorna H McNeill and 9 more

Abstract read
In one paragraph

Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Integrating Cancer Prevention into Science Education: Development of the CARES4You School-based Curriculum.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Robert A HiattDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California.ORCID 0000-0001-7174-8436
Amy E KennedyDivision of Cancer Control and Population Sciences, National Cancer Institute, Rockville, Maryland.ORCID 0000-0001-9589-5510
Alexandra K AdamsCenter for American Indian and Rural Health Equity, Montana State University, Bozeman, Montana.ORCID 0009-0004-0858-0000
Karen M Basen-EngquistDepartment of Health Disparities Research, The University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0001-7299-0646
Melissa L BondyDepartment of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, California.ORCID 0000-0002-0278-414X
Luis G Carvajal-CarmonaThe Health Equity Leadership, Science, and Community Lab (The LCC Lab), Genome Center, University of California, Davis, Davis, California.ORCID 0000-0001-7129-2918
Mona FouadDivision of General Internal Medicine and Population Science, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0002-3522-4835
David B GruskyDepartment of Sociology and Center on Poverty and Inequality, Stanford University, Stanford, California.ORCID 0000-0001-8469-2654
Phoenix MatthewsSchool of Nursing, Columbia University, New York, New York.ORCID 0000-0002-0074-681X
Lorna H McNeillDepartment of Health Disparities Research, The University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0003-1594-6301
Erica PhillipsDepartment of Medicine, Cancer Prevention and Control Program, The Meyer Cancer Center, Weill Cornell Medicine, New York, New York.ORCID 0000-0002-6803-2442
Laura C PinheiroDivision of General Internal Medicine, Department of Medicine, Weill Cornell Medicine, New York, New York.ORCID 0000-0002-6920-8526
Maria PisuDivision of General Internal Medicine and Population Science, Department of Medicine, O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0001-9329-3268
Ruth RechisCancer Prevention and Control Platform, The University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0002-9713-3541
David H RehkopfDepartment of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, California.ORCID 0000-0002-7597-6513
Rulla M TamimiDepartment of Population Health Sciences, Weill Cornell Medicine, New York, New York.ORCID 0000-0003-2306-8668
Mary Beth TerrySilent Spring Institute, Newton, Massachusetts.ORCID 0000-0002-4106-5033
David W WetterPopulation Health Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah.ORCID 0000-0002-4013-1932
Shobha SrinivasanDivision of Cancer Control and Population Sciences, National Cancer Institute, Rockville, Maryland.ORCID 0000-0003-1207-2645

Funding

RESEARCH METHODS COREU54CA280808 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Rulla M Tamimi · 2023 to 2026
$9.4M
Research and Methods CoreU54CA280812 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI GUILHERME DEL FIOL · 2023 to 2026
$9.3M
NCI NIH HHS U54 CA280808NCI NIH HHS U54 CA280812
6 · The paper itself

Abstract

Social determinants of health are known drivers of a broad range of cancer outcomes. These determinants influence factors at the structural and institutional levels of society, which disproportionately affects those living in persistent poverty. Americans living in persistent poverty areas experience higher cancer incidence, delayed cancer diagnosis and treatment, and greater cancer morbidity and mortality. This report describes the aims of the NCI's Persistent Poverty Initiative, a novel research program developed to study the association of structural and institutional factors that affect cancer outcomes in persistent poverty areas. The goals of the five funded centers located across the country are described. A detailed multilevel conceptual framework was developed to incorporate the perspectives of the five centers. The framework serves as a model for other researchers studying the complex social factors and pathways that contribute to cancer outcomes. Future research can build upon this work to integrate multilevel intervention models that can examine the association of upstream social determinants of health factors and cancer outcomes. The Persistent Poverty Initiative can serve as a model for addressing cancer outcomes at the structural and institutional levels, which will hopefully lead to improved local, state, and national strategies in an effort to achieve optimal health for all.

Indexed as

NeoplasmsPovertySocial Determinants of HealthHumansSocioeconomic FactorsUnited States

Identifiers

PMID40746119
PMCPMC13103677

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.