Evidence map›Paper›PMID 40745962›Full record

ArticleEuropean journal of haematology2025

Patient Characteristics, Healthcare Contacts and Drug Use in Polycythaemia Vera in Denmark.

Karoline Mathilde Lundgaard, Dustin Andersen Patel, Mette Brabrand, Christen Lykkegaard Andersen, Anton Pottegård

Abstract read
In one paragraph

Article in European journal of haematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karoline Mathilde LundgaardClinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health, University of Southern Denmark, Odense, Denmark.ORCID https://orcid.org/0009-0006-6413-9804
Dustin Andersen PatelThe Research Unit for General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0003-3996-0431
Mette BrabrandDepartment of Hematology, Odense University Hospital, Odense, Denmark.ORCID https://orcid.org/0000-0001-6282-5348
Christen Lykkegaard AndersenThe Research Unit for General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0001-7753-6768
Anton PottegårdClinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health, University of Southern Denmark, Odense, Denmark.ORCID https://orcid.org/0000-0001-9314-5679

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePatients with polycythaemia vera (PV) may experience symptoms and cardiovascular complications before receiving a diagnosis. Understanding the associated patterns of healthcare and drug utilisation may help detect patients who need diagnostic workup. In this study, we described healthcare contacts and prescription drug use in patients with PV in Denmark before and after their diagnosis.

methodsWe conducted a descriptive study using national Danish registries, matching patients with PV diagnosed between 2012 and 2021 (n = 1428) to the background population on age and sex.

resultsPatients with PV had a median age of 70 years [61-77] with an equal distribution of men and women. The patients were comparable to the comparison group across most characteristics except for a history of cardiovascular disease. In the 3 months before and 6 months after diagnosis, patients with PV had an increased number of healthcare contacts and rate of new drugs. The drug rate returned to baseline after 6 months, while outpatient contacts remained increased.

conclusionsPatients with PV experienced an increase in healthcare and drug utilisation around the time of diagnosis, but were comparable to the background population up to 3 months before, with no indicators allowing earlier detection of PV related to drug use or healthcare contacts.

Indexed as

Polycythemia VeraAgedDenmarkDrug UtilizationFemaleHumansMaleMiddle AgedRegistriesdrug utilisationhealth services utilisationpolycythaemia veraregistries

Identifiers

PMID40745962
PMCPMC12505824

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.