Evidence map›Paper›PMID 40745502›Full record

ArticleDiscover nano2025

Synthesis and characterization of honey bee venom-loaded calcium oxide nanocomposites and evaluation of their cytotoxic (MCF-7) and antifungal activity.

Vikram Jadhav, Arun Bhagare, Revannath Gurgude, Dnyaneshwar Lokhande, Shaktising Pardeshi, Jayraj Aher

Abstract read
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Article in Discover nano, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vikram JadhavDepartment of Chemistry, M. V. P. Samaj's K. K. Wagh Arts, Science, and Commerce College, SPPU, Pimpalgaon, Nashik, Maharashtra, 422209, India. mevikramjadhav@gmail.com.
Arun BhagareDepartment of Chemistry, M. V. P. Samaj's K. K. Wagh Arts, Science, and Commerce College, SPPU, Pimpalgaon, Nashik, Maharashtra, 422209, India.
Revannath GurgudeDepartment of Chemistry, Dalit Mitra Kadam Guruji Vidnyan Mahavidyalaya, Mangalwedha, Solapur, 413305, Maharashtra, India.
Dnyaneshwar LokhandePost Graduate Department of Chemistry, K. R. T. Arts, B. H. Commerce, and A. M. Science College, SPPU, Nashik, Maharashtra, 422002, India. ddlokhande1175@gmail.com.
Shaktising PardeshiKarmaveer Punjababa Goverdhane Arts, Commerce, and Science College Igatpuri, Nashik, Maharashtra, 422403, India.
Jayraj AherPost Graduate Department of Chemistry, K. R. T. Arts, B. H. Commerce, and A. M. Science College, SPPU, Nashik, Maharashtra, 422002, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, we studied a sonication-assisted method to synthesize Apis mellifera honey bee venom-loaded calcium oxide nanocomposites (BVNPs@CaO NCs). It effectively maintains the bioactivity and stability of the BV bioactive components on the surface of the CaO nanomaterials, showing potential bio-medicinal applications. The crude BV was purified and homogenized, and BVNPs were prepared via hydrothermal synthesis. At the same time, CaO nanomaterials were synthesized using an extract of Moringa oleifera leaves and combined with a sonication-assisted method to produce BVNPs@CaONCs. Using several characterizations, their irregular shape morphology was confirmed through TEM, revealing an interplanar spacing of 0.24 nm. The SAED pattern exhibited high crystallinity, as indicated by distinct diffraction rings and values of 7.26 (1/nm) and 6.38 (1/nm), corresponding to specific interplanar spacings within the crystal lattice/planes. The XRD analysis provided the crystal structure and revealed an average crystallite size of 31.47 nm. FTIR analysis shows O-H (3557 cm

Indexed as

Anticancer activityAntifungal activityApis melliferaBee venomCalcium oxideMCF-7 cells

Identifiers

PMID40745502
PMCPMC12314279

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.