Evidence map›Paper›PMID 40745387›Full record

ArticleCommunications medicine2025

The impact of prematurity on pediatric asthma morbidity and indices with environmental pollution and genetic susceptibility.

Jelte Kelchtermans, Frank Mentch, Huiqi Qu, Sharon A McGrath-Morrow, Hakon Hakonarson

Abstract read
In one paragraph

Article in Communications medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jelte KelchtermansChildren's Hospital of Philadelphia, Philadelphia, PA, USA. kelchtermj@chop.edu.ORCID http://orcid.org/0000-0001-9186-7547
Frank MentchChildren's Hospital of Philadelphia, Philadelphia, PA, USA.
Huiqi QuChildren's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0001-9317-4488
Sharon A McGrath-MorrowChildren's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0002-1576-5394
Hakon HakonarsonChildren's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0003-2814-7461

Funding

Translational Research Support CoreP30ES013508 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI A. Clementina Mesaros · 2006 to 2026
$35.3M
Clinical and Biochemical Features of Metabolic Dysregulation in Formerly Preterm ChildrenR01HL169859 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Eric Douglas Austin, Joseph Michael Collaco · 2024 to 2026
$2.2M
Critical Life Event supplement to 'Air pollution sensitivity in pediatric asthma'K08HL173625 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI Jelte Kelchtermans · 2025 to 2026
$317k
NHLBI NIH HHS K08 HL173625NHLBI NIH HHS R01 HL169859NIEHS NIH HHS P30 ES013508U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL169859
6 · The paper itself

Abstract

backgroundPrematurity, fine particulate matter (PM

methodsPediatric patients with asthma and at least 5 years of follow-up data were identified from the Center for Applied Genomics biobank. Subjects were classified as full term (FT), late preterm (LPT), or extremely/very preterm (E/VPT). PM

resultsAmong 5982 patients, 16% are LPT and 4% E/VPT. The latter patient group experiences 20.5% more exacerbations than FT patients (P = 0.04). E/VPT patients have 43.3% more exacerbations per unit increase in PM

conclusionsInteractions between prematurity, PM

Identifiers

PMID40745387
PMCPMC12314037

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.