Evidence map›Paper›PMID 40745383›Full record

ArticleScientific reports2025

Deep learning-driven brain tumor classification and segmentation using non-contrast MRI.

Nan-Han Lu, Yung-Hui Huang, Kuo-Ying Liu, Tai-Been Chen

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nan-Han LuDepartment of Radiology, E-DA Cancer Hospital, I-Shou University, No. 21, Yida Road, Jiao- Su Village, Yan-Chao District, Kaohsiung, 82445, Taiwan. leunanhan@seed.net.tw.
Yung-Hui HuangDepartment of Medical Imaging and Radiological Science, I-Shou University, No. 8, Yida Road, Jiao-Su Village, Yan-Chao District, Kaohsiung, 82445, Taiwan.
Kuo-Ying LiuDepartment of Radiology, E-DA Cancer Hospital, I-Shou University, No. 21, Yida Road, Jiao- Su Village, Yan-Chao District, Kaohsiung, 82445, Taiwan.
Tai-Been ChenDepartment of Radiological Technology, Teikyo University, Tokyo, 173-8605, Japan. ztbchen@outlook.com.

Funding

EDA Hospital, Taiwan EDCHP113010National Science and Technology Council in Taiwan NSTC 113-2221-E-214-007
6 · The paper itself

Abstract

This study aims to enhance the accuracy and efficiency of MRI-based brain tumor diagnosis by leveraging deep learning (DL) techniques applied to multichannel MRI inputs. MRI data were collected from 203 subjects, including 100 normal cases and 103 cases with 13 distinct brain tumor types. Non-contrast T1-weighted (T1w) and T2-weighted (T2w) images were combined with their average to form RGB three-channel inputs, enriching the representation for model training. Several convolutional neural network (CNN) architectures were evaluated for tumor classification, while fully convolutional networks (FCNs) were employed for tumor segmentation. Standard preprocessing, normalization, and training procedures were rigorously followed. The RGB fusion of T1w, T2w, and their average significantly enhanced model performance. The classification task achieved a top accuracy of 98.3% using the Darknet53 model, and segmentation attained a mean Dice score of 0.937 with ResNet50. These results demonstrate the effectiveness of multichannel input fusion and model selection in improving brain tumor analysis. While not yet integrated into clinical workflows, this approach holds promise for future development of DL-assisted decision-support tools in radiological practice.

Indexed as

Brain NeoplasmsDeep LearningImage Processing, Computer-AssistedMagnetic Resonance ImagingAdultAgedFemaleHumansMaleMiddle AgedNeural Networks, ComputerArtificial intelligenceBrain MRIConvolutional neural networks (CNNs)Deep learningFully convolutional networks (FCNs)Tumor classificationTumor segmentation

Identifiers

PMID40745383
PMCPMC12314025

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.