Evidence map›Paper›PMID 40745246›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

The association of the MIND diet and its components with cognitive function in postmenopausal breast cancer survivors.

Timothy R Winschel, Kellie Weinhold, Patrick M Schnell, Stephanie Gorka, Maryam Lustberg, Darrin Aase, Zihan Melink, Rachel Kopec, Chase Picino, Ziqi Li and 3 more

Abstract read
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Factors associated with programme completion and physical activity adherence in a community-based cancer exercise programme.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Timothy R WinschelHuman Nutrition Program, Department of Human Sciences, The Ohio State University, Columbus, OH, 43210, USA.
Kellie WeinholdHuman Nutrition Program, Department of Human Sciences, The Ohio State University, Columbus, OH, 43210, USA.
Patrick M SchnellDivision of Biostatistics, College of Public Health, The Ohio State University, Columbus, OH, 43210, USA.
Stephanie GorkaDepartment of Psychiatry and Behavioral Health, The Ohio State University Wexner Medical Center, Columbus, OH, 43210, USA.
Maryam LustbergYale School of Medicine, Center for Breast Cancer, New Haven, CT, 06511, USA.
Darrin AaseDepartment of Psychiatry and Behavioral Health, The Ohio State University Wexner Medical Center, Columbus, OH, 43210, USA.
Zihan MelinkHuman Nutrition Program, Department of Human Sciences, The Ohio State University, Columbus, OH, 43210, USA.
Rachel KopecHuman Nutrition Program, Department of Human Sciences, The Ohio State University, Columbus, OH, 43210, USA.
Chase PicinoCollege of Pharmacy, The Ohio State University, Columbus, OH, 43210, USA.
Ziqi LiDepartment of Food Science and Technology, The Ohio State University, Columbus, OH, 43210, USA.
Bridget OppongDepartment of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Nicole WilliamsDepartment of Medical Oncology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Tonya S OrchardHuman Nutrition Program, Department of Human Sciences, The Ohio State University, Columbus, OH, 43210, USA. orchard.6@osu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCancer related cognitive impairment is frequently reported by cancer survivors. The purpose of this study was to determine the association of the MIND diet pattern and its components with cognitive function in breast cancer survivors following chemotherapy.

methodsThis was a cross-sectional study of 30 post-menopausal breast cancer survivors within one year of completing chemotherapy; 21 had complete data for analysis. Cognitive outcomes were assessed using a battery of objective tests. Self-reported dietary data were collected through electronic food frequency questionnaire; nutritional biomarkers were measured in blood. Linear regression models assessed the associations between the MIND diet score and its components with cognitive outcomes.

resultsAdherence to the MIND diet pattern was positively associated with global cognitive score (β = 1.163, p = 0.013), episodic memory (β = 3.726, p = 0.019), attention/working memory (β = 4.046, p = 0.024) and phonemic fluency (β = 42.305, p = 0.002) adjusting for education and total energy intake. Foods emphasized in the MIND diet such as non-fried fish, vegetables, and beans/legumes were all positively associated with cognitive performance on individual tests (p < 0.05 for all). Blood biomarkers of vegetable (β-carotene) and non-fried fish (docosahexaenoic acid (DHA)) correlated with self-reported intake. Blood DHA was correlated with better cognitive performance (p < 0.05) Additionally, moderate intake of red meat and lower intake of fast food were positively associated with cognitive performance (p < 0.05 for both).

conclusionsAmong post-menopausal breast cancer survivors that are within one year of completing chemotherapy, adherence to the MIND diet pattern and its components was associated with better cognitive function.

Indexed as

Breast NeoplasmsCancer SurvivorsCognitionCognitive DysfunctionDietAgedCross-Sectional StudiesFemaleHumansLinear ModelsMiddle AgedPostmenopauseBreast cancerCancer related cognitive impairmentChemotherapyMIND diet

Identifiers

PMID40745246
PMCPMC12313734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.