ReviewAdvances in experimental medicine and biology2025
Drosophila as a Model for Metastasis.
Review in Advances in experimental medicine and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metastasis, the spread of cancer from the primary tumor to distant sites, accounts for the majority of cancer-related deaths. This complex process involves tumor cell detachment, invasion into surrounding tissues, entry into blood vessels, survival in circulation, and colonization of secondary sites. Key factors in metastasis include changes in cell proliferation, loss of anchorage dependence, and activation of oncogenic pathways. While much has been learned from mammalian models, particularly mice, many aspects remain poorly understood. The Drosophila model offers unique advantages, with its powerful genetic tools, whole-organism imaging capabilities, and insights into host-tumor interactions, to advance our knowledge of the key processes that drive metastatic events. Multispecies approaches, including Drosophila, are essential for advancing our understanding of metastasis and may lead to breakthroughs not achievable through single-species studies.
Indexed as
Identifiers
40745140What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.