ReviewRadiologie (Heidelberg, Germany)2025
[Osteomyelitis in adults].
Review in Radiologie (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOsteomyelitis (OM) refers to inflammatory diseases of the bone caused by microorganisms. A continuous increase in the prevalence of osteomyelitis has been observed. Despite advances in medical care, early diagnosis remains challenging due to initially nonspecific symptoms, particularly in elderly or immunocompromised patients.
objectiveThis article aims to provide a structured overview of the pathogenesis of OM, the role of imaging, and the most important differential diagnoses.
methodsNarrative, literature-based review incorporating current guidelines, radiological protocols, and imaging characteristics.
resultsMagnetic resonance imaging (MRI) is the diagnostic gold standard. It enables early detection of bone marrow edema and inflammatory changes. The "penumbra sign" and the "ghost sign" contribute in distinguishing tumors and Charcot arthropathy, respectively. Computed tomography (CT) is essential for chronic OM and sequestrum detection. Flourodeoxyglucose-18 positron emission tomography (FDG-PET) can be helpful in unclear cases, particularly in patients with prosthetic implants.
conclusionA multidisciplinary, imaging-guided approach is critical for early diagnosis, treatment planning, and follow-up in OM. Radiological signs such as the penumbra and ghost signs assist in differentiating from other conditions. Advances in MRI techniques (e.g., zero time echo [ZTE] sequences) and the use of hybrid nuclear medicine procedures expand diagnostic capabilities, enhance surgical planning, and optimize therapy and follow-up.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.