ArticleJournal of nephrology2025
Efficacy and safety of antithrombotics in patients with atrial fibrillation undergoing hemodialysis: a nationwide cohort study in Korea.
Article in Journal of nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Oral anticoagulation and left atrial appendage closure in dialysis atrial fibrillation: between stroke prevention and bleeding hazard.Clinical kidney journal · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAtrial fibrillation and chronic kidney disease mutually interact, presenting distinct clinical dilemmas where the optimal risk-benefit profile of antithrombotic therapy remains undefined.
methodsThis study was conducted using the Korean Health Insurance Review and Assessment Service database in patients with atrial fibrillation undergoing hemodialysis. The primary outcomes included thromboembolism and intracranial hemorrhage rates, while major bleeding and all-cause death were secondary outcomes. Selecting patients not taking antithrombotics as a reference, Kaplan-Meier and Cox proportional hazard analyses were performed for those taking antiplatelets, direct oral anticoagulants (DOACs), and warfarin. The net clinical benefit was obtained by balancing the efficacy and safety of each antithrombotic therapy.
resultsThere were 13,311 patients on hemodialysis recorded as with atrial fibrillation, the mean age was 63.1 ± 12.8 years, with the mean CHA
conclusionThis study provides real-world evidence on the use of antithrombotic therapy in atrial fibrillation patients undergoing hemodialysis. The findings highlight the profound complexity and uncertainty in managing this high-risk population, underscoring the importance for comprehensive assessment, individualized treatment approaches, and further dedicated research to establish optimal prevention and treatment strategies.
Indexed as
Identifiers
40745057What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.