ArticleScientific reports2025
A large-scale case-control study on the association between dietary fat quality indices and risk of breast cancer.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The relationship between breast cancer (BC) and total dietary and types of fat is well-established, however, the association with dietary fat quality (DFQ) indices remains to be elucidated. Therefore, the aim was to investigate the associations between DFQ indices and odds of BC among women. This hospital-based case-control study included 464 women with pathologically confirmed BC during the past year and 498 apparently healthy controls of similar age and residence. Dietary intake was assessed using a validated food frequency questionnaire (FFQ) and DFQ indices were calculated. The likelihood of BC was evaluated across tertiles of specific DFQ indices scores [atherogenicity index (AI), thrombogenic index (TI), hypo- and hypercholesterolemic fatty acids ratio (h/H), omega-3 to omega-6 polyunsaturated fatty acids ratio (∑ω-3/∑ω-6), polyunsaturated fatty acids/saturated fatty acids ratio (PSR), dietary lipophilic index (LI), cholesterol/saturated fat index (CSI)]. After controlling for several potential confounders, CSI was inversely associated with BC risk among all participants (OR: 0.53, 95% CI: 0.37-0.76; P = 0.001). This association remained significant after stratified analysis in pre-postmenopausal women. In addition, there were higher odds of BC in the highest category of PSR compared to the lowest category in among postmenopausal women (OR: 1.93; 95% CI: 1.07-3.48 P = 0.03). There were no other significant associations between BC risk and the other DFQ indices.PSR and CSI might be directly and inversely associated with the odds of BC, respectively. To confirm the causality of the associations, prospective cohort studies are needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.