ArticleJournal of applied clinical medical physics2025
Tumor-driven SRS VMAT planning: Regression models for intermediate and low dose spillage.
Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Memory circuit dosimetry in patients with brain metastases treated with Sparing Memory with Advanced Radiosurgery Targeting (SMART) technique.Clinical and translational radiation oncology · 2026Article
- Modeling dose to normal brain following hypofractionated stereotactic radiotherapy to a single brain metastasis.Journal of applied clinical medical physics · 2026Article
- Tumor-driven SRS VMAT planning: Regression models for intermediate and low dose spillage.Journal of applied clinical medical physics · 2025Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeStereotactic radiosurgery (SRS) for brain metastases using volumetric modulated arc therapy (VMAT) is increasingly utilized. While high-dose conformity guidelines relative to tumor volume exist, recommendations for intermediate and low-dose regions remain undefined. This study explores tumor-specific characteristics and new dosimetric parameters to develop regression models for standardizing intracranial SRS planning. MATERIALS AND
methodWe introduce two dosimetric quantities: R
resultsStrong correlations were found between PTV
conclusionThis study proposes regression-based models for predicting dose spill based on tumor burden, total PTV volume and number of targets. These models provide a framework for model-based SRS planning, offering clinical physicists patient-specific guidance to improve consistency, optimize plan quality, and support future standardization efforts.
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Registered trials
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