Evidence map›Paper›PMID 40744832›Full record

ReviewTrends in molecular medicine2026

Autoantibodies as drivers of neuropathic pain.

Adham Farah, Omar Daifallah, Evanka Singh, John M Dawes

Abstract readReview
In one paragraph

Review in Trends in molecular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Recent advances in autoantibody-mediated pain.Current opinion in supportive and palliative care · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Adham FarahNuffield Department of Clinical Neurosciences, University of Oxford, OX3 9DU, UK.
Omar DaifallahNuffield Department of Clinical Neurosciences, University of Oxford, OX3 9DU, UK; Department of Zoology, King Saud University, Riyadh, Saudi Arabia.
Evanka SinghNuffield Department of Clinical Neurosciences, University of Oxford, OX3 9DU, UK.
John M DawesNuffield Department of Clinical Neurosciences, University of Oxford, OX3 9DU, UK. Electronic address: john.dawes@ndcn.ox.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging evidence, supported by clinical responses to immunotherapy and the recapitulation of sensory symptoms in passive transfer models, shows that autoantibodies (AAbs) may drive neuropathic pain. These findings highlight the importance of immune profiling to enhance diagnosis and treatment, and provide molecular insights into broader pain mechanisms in clinical contexts.

Indexed as

AutoantibodiesNeuralgiaAnimalsHumansAutoantibodies

Identifiers

PMID40744832
PMCPMC13328050

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.