Evidence map›Paper›PMID 40744493›Full record

ArticleNucleic acids research2025

Electro-switchable addressing system for achieving repetitive random data access.

Haotian Yu, Yemin Han, Weiming Lin, Han Gao, Weihao Li, Manman Lv, Mengqing Cheng, Yan Huang, Kun Bi, Zuhong Lu and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nucleic acids research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Haotian YuState Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.
Yemin HanState Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.
Weiming LinState Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.
Han GaoState Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.
Weihao LiState Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.
Manman LvState Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.
Mengqing ChengState Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.
Yan HuangState Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.
Kun BiState Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.ORCID 0000-0002-1827-7572
Zuhong LuState Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.
Quanjun LiuState Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.ORCID 0000-0003-2706-2191

Funding

National Key Research and Development Project 2020YFA0712104National Natural Science Foundation of China 61827814National Natural Science Foundation of China 62201141Shenzhen Science and Technology Program JCYJ20220530160416036Shenzhen Science and Technology Program JCYJ20230807114612024
6 · The paper itself

Abstract

Due to its high physical density and excellent durability, DNA data storage has become an attractive storage solution. Efficient and fast random access to the required storage data is a key element of any data storage system. Here, we present a method of using electrically driven DNA conformation to promote or inhibit T7 promoter transcription in order to random access DNA information. Electrical actuation provides physical addresses for accessing specific information without the need to design complex sequence address sets to expand the space of encoded sequences and increase theoretical storage density and capacity. At the same time, the T7 promoter transcribes DNA information in situ without damaging DNA, achieving multiple information reads with one write. In addition, the random access to the electrode array chip reveals the possibility of future compatibility with DNA synthesis, laying the foundation for future miniaturized storage integration.

Indexed as

DNAInformation Storage and RetrievalElectrodesNucleic Acid ConformationPromoter Regions, GeneticTranscription, GeneticDNA

Identifiers

PMID40744493
PMCPMC12311788

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.