Evidence map›Paper›PMID 40744467›Full record

ArticleBJPsych open2025

Rapid tranquillisation for psychiatric in-patients with a diagnosis of personality disorder: under-recognised issue.

Carol Paton, Mike J Crawford, Matthew Hartley, Clive E Adams, Elena M Edokpolor Pernia, Olivia Rendora, Thomas R E Barnes

Abstract read
In one paragraph

Article in BJPsych open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carol PatonPrescribing Observatory for Mental Health, Royal College of Psychiatrists, London, UK.ORCID https://orcid.org/0000-0001-7756-1031
Mike J CrawfordDivision of Psychiatry, Imperial College London, London, UK.ORCID https://orcid.org/0000-0003-3137-5772
Matthew HartleyBehavioural & Developmental Psychiatry Clinical Academic Group, South London and Maudsley NHS Foundation Trust, London, UK.ORCID https://orcid.org/0000-0003-2522-7781
Clive E AdamsMental Health Services Research. University of Nottingham, Nottingham, UK.ORCID https://orcid.org/0000-0003-1628-4020
Elena M Edokpolor PerniaPrescribing Observatory for Mental Health, Royal College of Psychiatrists, London, UK.ORCID https://orcid.org/0009-0000-8903-3201
Olivia RendoraPrescribing Observatory for Mental Health, Royal College of Psychiatrists, London, UK.ORCID https://orcid.org/0000-0002-7843-3426
Thomas R E BarnesPrescribing Observatory for Mental Health, Royal College of Psychiatrists, London, UK.ORCID https://orcid.org/0000-0002-2324-656X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClinical guidelines for personality disorder emphasise the importance of patients being supported to develop psychological skills to help them manage their symptoms and behaviours. But where these mechanisms fail, and hospital admission occurs, little is known about how episodes of acutely disturbed behaviour are managed.

aimsTo explore the clinical characteristics and management of episodes of acutely disturbed behaviour requiring medication in in-patients with a diagnosis of personality disorder.

methodAnalysis of clinical audit data collected in 2024 by the Prescribing Observatory for Mental Health, as part of a quality improvement programme addressing the pharmacological management of acutely disturbed behaviour. Data were collected from clinical records using a bespoke proforma.

resultsSixty-two mental health Trusts submitted data on 951 episodes of acutely disturbed behaviour involving patients with a personality disorder, with this being the sole psychiatric diagnosis in 471 (50%). Of the total, 782 (82%) episodes occurred in female patients. Compared with males, episodes in females were three times more likely to involve self-harming behaviour or be considered to pose such a risk (22% and 70% respectively:

conclusionsOur findings suggest that there are a large number of episodes of acutely disturbed behaviour on psychiatric wards in women with a diagnosis of personality disorder. These episodes are characterised by self-harm and regularly prompt the administration of rapid tranquillisation. This has potential implications for service design, staff training, and research.

Indexed as

acutely disturbed behaviourPersonality disorderrapid tranquillisationself-harm

Identifiers

PMID40744467
PMCPMC12344434

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.