Evidence map›Paper›PMID 40744359›Full record

ArticleThe Journal of physiology2025

Non-ventilatory events substantially contribute to rise in pulmonary arterial blood flow with early or delayed cord clamping at birth in preterm lambs.

Joseph J Smolich

Abstract read
In one paragraph

Article in The Journal of physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Joseph J SmolichHeart Research, Murdoch Children's Research Institute, Parkville, Victoria, Australia.ORCID 0000-0002-7363-0172

Funding

Federal Government | DHAC | National Health and Medical Research Council (NHMRC) 1105137Victorian Government's Operational Infrastructure Support Program
6 · The paper itself

Abstract

A widely held view is that an increased pulmonary arterial (PA) blood flow at birth is not triggered until the onset of lung aeration, but experimental data indicate that the non-ventilatory events of a reduction in lung liquid volume, complete fetal delivery, and umbilical cord clamping can also increase fetal PA flow. However, the effect of cord clamping strategy on the contribution of these non-ventilatory events to birth-related rises in PA flow is unknown. Accordingly, PA blood flow was measured via transit-time flow probe in anaesthetized, acutely instrumented preterm fetal lambs at baseline, after a ∼35% reduction in lung liquid volume, following complete fetal delivery, and then after (1) delayed cord clamping (DCC) preceded by ventilation lasting ∼100 s (n = 11), or (2) early cord clamping (ECC) followed by either a non-asphyxial (∼35 s, n = 10) or an asphyxial interval (∼100 s,

Indexed as

Pulmonary ArteryPulmonary CirculationUmbilical Cord ClampingAnimalsAnimals, NewbornFemaleLungPregnancyPremature BirthSheepUmbilical Cordbirth transitiondelayed cord clampingearly cord clampingfetal deliverylung liquid volumepulmonary arterial blood flow

Identifiers

PMID40744359
PMCPMC12369308

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.