Evidence map›Paper›PMID 40744257›Full record

ArticleThe Journal of allergy and clinical immunology2025

Neighborhood disadvantage and the back-to-school epidemic of viral-associated asthma exacerbations.

Darlene Bhavnani, Peter Dunphy, Sarah Chambliss, Daniel S W Katz, Emily Hall, Rebecca A Zárate, Susan Balcer-Whaley, Paul J Rathouz, Elizabeth C Matsui

Abstract read
In one paragraph

Article in The Journal of allergy and clinical immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Darlene BhavnaniDepartment of Population Health, Dell Medical School, University of Texas at Austin, Austin, Tex. Electronic address: Darlene.Bhavnani@Austin.utexas.edu.
Peter DunphyDepartment of Government, University of Texas at Austin, Austin, Tex.
Sarah ChamblissDepartment of Population Health, Dell Medical School, University of Texas at Austin, Austin, Tex.
Daniel S W KatzSchool of Integrative Plant Science, Cornell University, Ithaca, NY.
Emily HallDepartment of Population Health, Dell Medical School, University of Texas at Austin, Austin, Tex.
Rebecca A ZárateDepartment of Population Health, Dell Medical School, University of Texas at Austin, Austin, Tex.
Susan Balcer-WhaleyDepartment of Population Health, Dell Medical School, University of Texas at Austin, Austin, Tex.
Paul J RathouzDepartment of Population Health, Dell Medical School, University of Texas at Austin, Austin, Tex.
Elizabeth C MatsuiDepartment of Population Health, Dell Medical School, University of Texas at Austin, Austin, Tex.

Funding

Outcome Dependent Sampling Studies of Longitudinal Data: Design and AnalysisR01HL094786 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jonathan Scott Schildcrout · 2009 to 2026
$6.1M
Institutional Career Development Core (KL2)KL2TR002646 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI TSEVAT, JOEL · 2018 to 2022
$3.4M
Environmental Control as Add-on Therapy in Urban Children with AsthmaR01ES023447 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI MATSUI, ELIZABETH C. · 2014 to 2018
$3.4M
Urban planning, siting of air pollution sources, and asthma disparitiesR01ES034803 · NIEHS · UNIVERSITY OF TEXAS AT AUSTIN · PI Elizabeth C. Matsui, ROGER PENG · 2023 to 2026
$2.1M
Childhood Asthma: Disease Course and Lung Function Trajectories and Air Pollution ExposureR01ES035131 · NIEHS · UNIVERSITY OF TEXAS AT AUSTIN · PI Elizabeth C. Matsui, ROGER PENG · 2024 to 2026
$2.0M
NCATS NIH HHS KL2 TR002646NHLBI NIH HHS R01 HL094786NIEHS NIH HHS R01 ES023447NIEHS NIH HHS R01 ES034803NIEHS NIH HHS R01 ES035131
6 · The paper itself

Abstract

backgroundRates of viral-associated asthma exacerbations typically increase when children return to school after the summer holiday. The effect of neighborhood disadvantage on this back-to-school increase in viral-associated asthma exacerbations is unknown.

objectiveWe aimed to evaluate the effect of neighborhood disadvantage on the back-to-school increase in asthma-related emergency department (ED) visits.

methodsAdministrative health records were used to define population-based incidence rates of asthma-related ED visits by week and census tract among children aged 5 to 17 years. Using Bayesian regression models of incidence rates, we evaluated additive interactions between a 7-week back-to-school period (relative to a 6-week summer period) and neighborhood disadvantage (eg, captured by the Social Vulnerability Index [SVI]).

resultsIn census tracts with low social vulnerability (SVI = 2), rates of asthma-related ED visits increased by an average of 378 (95% credible interval [CrI] = 358-398) per 100,000 person years when children went back to school. Relative to the back-to-school increase in tracts with low social vulnerability, in tracts with moderate social vulnerability (SVI = 5) there was an excess of 199 asthma-related ED visits per 100,000 person years (95% CrI = 183-214). Relative to the back-to-school increase in tracts with moderate social vulnerability, in tracts with high social vulnerability (SVI = 8), there was an excess of 303 (95% CrI = 268-339) asthma-related ED visits per 100,000 person years.

conclusionGreater levels of neighborhood disadvantage were associated with a greater increase in the rate of asthma-related ED visits when children returned to school. Neighborhood disadvantage may modify the back-to-school increase in asthma exacerbations by increasing the risk of upper respiratory viral infections.

Indexed as

AsthmaVirus DiseasesAdolescentChildChild, PreschoolEmergency Service, HospitalFemaleHumansIncidenceMaleNeighborhood CharacteristicsResidence CharacteristicsSchoolsSocial Vulnerabilityasthma epidemichealth disparitiesNeighborhood disadvantageupper respiratory infectionviral-associated asthma exacerbationsviral transmission

Identifiers

PMID40744257
PMCPMC13485333

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.