ArticleNeuron2025
Representations of stimulus features in the ventral hippocampus.
Article in Neuron, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Amygdalostriatal transition zone neurons encode sustained cue responses to guide defensive behaviors.Neuron · 2026Article
- The ventral hippocampus: computations, circuits and functions.Nature reviews. Neuroscience · 2026Review
- vCA1 SST neurons represent avoidance states that guide anxiety-related behavioral choices.bioRxiv : the preprint server for biology · 2026Article
- Dentate Gyrus Engrams in Fear and Reward: Mechanistic Principles, Critical Gaps, and Paths to Translation.Journal of neurochemistry · 2026Review
- Bridging neurobiological mechanisms and translational applications in cognitive science: inspirations from the MCCS-NYUAD meeting 2025.Molecular brain · 2026Review
- Multiple-Context Training Enhances Generalization of Cued Fear Extinction and Requires the Dorsal Hippocampus.bioRxiv : the preprint server for biology · 2026Article
- Discrete and differentiated encoding of distinct components of spatial experience occurs within the proximodistal subfields of the dorsoventral axis of the hippocampus.Frontiers in behavioral neuroscience · 2026Article
- Emotional shaping of spatial encoding along the dorsal ventral axis of the hippocampus.Frontiers in systems neuroscience · 2026Review
- Anxiety and Beyond: Diversity in Ventral Hippocampus Circuits and Function.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Hippocampal transformations occur along dimensions of memory interference.bioRxiv : the preprint server for biology · 2025Article
- Negative results positive for understanding the neural representation of valence across the brain.Neuron · 2025Article
Corrections and comments
- Update of
Authors and funding
10 authors.
Funding
Abstract
Discriminating and categorizing the meaning of environmental stimuli and responding accordingly are essential for survival. The ventral hippocampus (vHPC) controls emotional and motivated behaviors in response to environmental cues and is hypothesized to do so in part by deciphering the positive or negative quality of these cues. Yet, what features of the environment are represented in the activity patterns of ventral CA1 (vCA1) neurons and whether the positive or negative meaning of stimuli is present at this stage remain unclear. Here, using two-photon calcium imaging across six experimental paradigms, we examined which features of salient stimuli are represented by vCA1 ensembles and found that identity, sensory features, and intensity-but not valence-are robustly encoded. These results offer a reappraisal of the vCA1 function, wherein information corresponding to individual stimulus features, and not their meaning, predominates. This organizational scheme may support flexible updating of stimulus value as internal states and environmental demands change.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.