Evidence map›Paper›PMID 40743909›Full record

ReviewInternational archives of allergy and immunology2026

Pollen-Food Allergy Syndrome in China: Current Knowledge and Future Research Needs.

Nannan Jiang, Shan Deng, Kai Guan, Li Xiang

Abstract readReview
In one paragraph

Review in International archives of allergy and immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nannan JiangDepartment of Allergy, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Key Laboratory of Major Diseases in Children, Ministry of Education, China National Clinical Research Center for Respiratory Diseases, Beijing, China.
Shan DengDepartment of Allergy, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
Kai GuanDepartment of Allergy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment of Allergic Disease, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing, China, dr_guankai@126.com.
Li XiangDepartment of Allergy, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Key Laboratory of Major Diseases in Children, Ministry of Education, China National Clinical Research Center for Respiratory Diseases, Beijing, China, dr_xiangli2022@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

<p>Background: Pollen-food allergy syndrome (PFAS) is a distinct form of IgE-mediated food allergy that occurs in individuals sensitized to pollen. The characteristics of PFAS vary across regions and exhibit significant heterogeneity due to differing pollen sensitization profiles. Summary: Research on PFAS in China has primarily focused on Northern regions, where weed and tree pollen allergy, particularly to Artemisia, are prevalent. PFAS is more commonly observed in China among patients allergic to Artemisia pollen, nsLTPs (e.g., Art v 3) derived from Artemisia pollen is regarded as a biomarker for severe food-pollen allergies in China. Other cross-reactive components, including PR-10, profilins, and recently identified GRP, also contribute to PFAS. Diagnosis mainly relies on clinical history, supported by specific IgE, skin prick testing, and component-resolved diagnostics (CRD), while management includes dietary modifications, allergen avoidance, and epinephrine for anaphylaxis. Although allergen immunotherapy and biologics have been explored, their efficacy remains limited, highlighting unmet needs for further research. Critical knowledge gaps persist in understanding PFAS epidemiology, risk factors, and regional variations in China. Future priorities include large-scale epidemiological studies, validation of diagnostic tools, and the development of tailored management guidelines for China's diverse population. Key Messages: This review aimed to provide a comprehensive overview of PFAS and its management to enhance understanding of the existing knowledge gaps and future research needs in China. </p>.

Indexed as

Food HypersensitivityPollenRhinitis, Allergic, SeasonalAllergensChinaCross ReactionsHumansImmunoglobulin EOral Allergy SyndromePrevalenceSyndromeAllergensImmunoglobulin EComponent-resolved diagnosisFood allergyPollen-food allergy syndrome

Identifiers

PMID40743909
PMCPMC12503661

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.