Evidence map›Paper›PMID 40743484›Full record

ArticleACS nano2025

Disrupting Biofilm Tolerance by Ionic Microbubble-Mediated Copper Ion Surge for Infection Clearance.

Xiaoye Li, Qiang Li, Ao He, Meng Dang, Yu Zhang, Minjin Wang, Qinhong Sun, Zhuo Dai, Meng Ding, Jingben Zheng and 3 more

Abstract read
In one paragraph

Article in ACS nano, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. CuBioactive materials · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Targeting multidrug-resistantMaterials today. Bio · 2026
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xiaoye LiNanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, 30 Zhongyang Road, Nanjing 210008, China.
Qiang LiNanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, 30 Zhongyang Road, Nanjing 210008, China.
Ao HeNanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, 30 Zhongyang Road, Nanjing 210008, China.
Meng DangNanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, 30 Zhongyang Road, Nanjing 210008, China.
Yu ZhangNanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, 30 Zhongyang Road, Nanjing 210008, China.
Minjin WangNanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, 30 Zhongyang Road, Nanjing 210008, China.
Qinhong SunDepartment of Thoracic Surgery, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & Nanjing Medical University Affiliated Cancer Hospital, Nanjing 210009, China.
Zhuo DaiNanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, 30 Zhongyang Road, Nanjing 210008, China.
Meng DingNanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, 30 Zhongyang Road, Nanjing 210008, China.
Jingben ZhengNanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, 30 Zhongyang Road, Nanjing 210008, China.
Yongbin MouNanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, 30 Zhongyang Road, Nanjing 210008, China.
Weijun XiuDepartment of Biomedical Engineering (BME), National University of Singapore, 15 Kent Ridge Cres, Singapore 119276, Singapore.
Heng DongNanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, 30 Zhongyang Road, Nanjing 210008, China.ORCID 0000-0002-2537-7950

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial infections caused by drug-resistant bacteria persist due to biofilm-mediated tolerance, which limits the efficacy of both antimicrobial agents and host immune defenses. Here, we develop ionic microbubbles (MB-CuTA) self-assembled by Fe

Indexed as

Anti-Bacterial AgentsBiofilmsCopperMicrobubblesAnimalsHumansIonsMiceMicrobial Sensitivity TestsPeritonitisAnti-Bacterial AgentsCopperIonsbiofilm tolerancecuproptosis-like deathimmuneintracellular bacterial clearancemicrobubble

Identifiers

PMID40743484
PMCPMC12356198

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.