Evidence map›Paper›PMID 40743458›Full record

Observational studyJournal of the American Medical Informatics Association : JAMIA2026

Predicting intracranial pressure monitor placement in children with traumatic brain injury: a prospective cohort study to develop a clinical decision support tool.

Seth Russell, Peter E DeWitt, Laura Helmkamp, Kathryn Colborn, Charlotte Gray, Margaret Rebull, Yamila L Sierra, Rachel Greer, Lexi Petruccelli, Sara Shankman and 4 more

Abstract readObservational Study
In one paragraph

Observational study in Journal of the American Medical Informatics Association : JAMIA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Seth RussellDepartment of Biomedical Informatics, University of Colorado School of Medicine, Aurora, CO 80045, United States.ORCID 0000-0002-2436-1367
Peter E DeWittDepartment of Biomedical Informatics, University of Colorado School of Medicine, Aurora, CO 80045, United States.ORCID 0000-0002-6391-0795
Laura HelmkampAdult and Child Center for Health Outcomes Research and Delivery Science (ACCORDS), University of Colorado School of Medicine, Aurora, CO 80045, United States.
Kathryn ColbornAdult and Child Center for Health Outcomes Research and Delivery Science (ACCORDS), University of Colorado School of Medicine, Aurora, CO 80045, United States.
Charlotte GrayChildren's Hospital Colorado Research Institute, Aurora, CO 80045, United States.
Margaret RebullDepartment of Biomedical Informatics, University of Colorado School of Medicine, Aurora, CO 80045, United States.
Yamila L SierraDepartment of Medicine, University of Colorado School of Medicine, Aurora, CO 80045, United States.
Rachel GreerChildren's Hospital Colorado Research Institute, Aurora, CO 80045, United States.
Lexi PetruccelliChildren's Hospital Colorado Research Institute, Aurora, CO 80045, United States.
Sara ShankmanChildren's Hospital Colorado Research Institute, Aurora, CO 80045, United States.
Todd C HankinsonAdult and Child Center for Health Outcomes Research and Delivery Science (ACCORDS), University of Colorado School of Medicine, Aurora, CO 80045, United States.
Fuyong XingDepartment of Biostatistics and Informatics, Colorado School of Public Health, Aurora, CO 80045, United States.
David J AlbersDepartment of Biomedical Informatics, University of Colorado School of Medicine, Aurora, CO 80045, United States.ORCID 0000-0002-5369-526X
Tellen D BennettDepartment of Biomedical Informatics, University of Colorado School of Medicine, Aurora, CO 80045, United States.ORCID 0000-0003-1483-4236

Funding

Effectiveness of ICP Monitoring in Pediatric Traumatic Brain InjuryK23HD074620 · NICHD · UNIVERSITY OF UTAH · PI BENNETT, TELLEN · 2013 to 2017
$701k
Archiving Common Data Element-Harmonized Pediatric Traumatic Brain Injury Data and MetadataR03HD094912 · NICHD · UNIVERSITY OF COLORADO DENVER · PI BENNETT, TELLEN · 2018 to 2019
$156k
Colorado Department of Human ServicesMindsource Brain Injury NetworkMindsource Brain Injury Network of the Colorado Department of Human ServicesNICHD NIH HHS K23 HD074620NICHD NIH HHS R03 HD094912
6 · The paper itself

Abstract

objectiveClinicians currently make decisions about placing an intracranial pressure (ICP) monitor in children with traumatic brain injury (TBI) without the benefit of an accurate clinical decision support tool. The goal of this study was to develop and validate a model that predicts placement of an ICP monitor and updates as new information becomes available. MATERIALS AND

methodsA prospective observational cohort study was conducted from September 2014 to January 2024. The setting included one US hospital designated as an American College of Surgeons Level 1 Pediatric Trauma Center. Participants were 389 children with acute TBI admitted to the ICU who had at least one Glasgow Coma Scale (GCS) score ≤ 8 or intubation with at least one GCS-Motor ≤ 5. We excluded children who received ICP monitors prior to arrival, those with GCS = 3 and bilateral fixed, dilated pupils, and those with a do not resuscitate order.

resultsOf the 389 participants, 138 received ICP monitoring. Several machine learning models, including a recurrent neural network (RNN), were developed and validated using 4 combinations of input data. The best performing model, an RNN, achieved an F1 of 0.71 within 720 minutes of hospital arrival. The cumulative F1 of the RNN from minute 0 to 720 was 0.61. The best performing non-neural network model, standard logistic regression, achieved an F1 of 0.36 within 720 minutes of hospital arrival.

conclusionsThese findings will contribute to design and implementation of a multidisciplinary clinical decision support tool for ICP monitor placement in children with TBI.

Indexed as

Brain Injuries, TraumaticDecision Support Systems, ClinicalIntracranial PressureAdolescentChildChild, PreschoolFemaleGlasgow Coma ScaleHumansInfantMachine LearningMaleMonitoring, PhysiologicNeural Networks, ComputerProspective Studiesclinical decision supportintracranial hypertensionintracranial pressuremachine learningpediatricstraumatic brain injury

Identifiers

PMID40743458
PMCPMC12758473

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.