Evidence map›Paper›PMID 40743404›Full record

SynthesisClinical and experimental dental research2025

Effectiveness of Endoscope-Assisted Subgingival Debridement Versus Repeated Root Surface Debridement or Access Flap Periodontal Surgery in Step 3 Periodontal Therapy: A Systematic Review and Meta-Analysis.

King-Lun Dominic Ho, Melissa Rachel Fok, Kar Yan Li, Georgios Pelekos, Wai Keung Leung

Abstract readSystematic ReviewMeta-AnalysisComparative Study
In one paragraph

Synthesis in Clinical and experimental dental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

King-Lun Dominic HoPeriodontology and Implant Dentistry, Faculty of Dentistry, the University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0003-1924-4278
Melissa Rachel FokPeriodontology and Implant Dentistry, Faculty of Dentistry, the University of Hong Kong, Hong Kong SAR, China.
Kar Yan LiClinical Research Centre, Faculty of Dentistry, the University of Hong Kong, Hong Kong SAR, China.
Georgios PelekosPeriodontology and Implant Dentistry, Faculty of Dentistry, the University of Hong Kong, Hong Kong SAR, China.
Wai Keung LeungPeriodontology and Implant Dentistry, Faculty of Dentistry, the University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0003-1979-910X

Funding

This study was supported by the Health and Medical Research Fund of Hong Kong (grant No. 18170492).
6 · The paper itself

Abstract

objectivesPeriodontitis is a multifactorial inflammatory disease leading to the progressive destruction of the tooth-supporting apparatus. The management of residual periodontal pockets remains a challenge for Step 3 periodontal therapy. This systematic review aims to evaluate the potential and efficacy of the periodontal endoscope in managing residual periodontal pockets during Step 3 periodontal therapy. MATERIAL AND

methodsA comprehensive search was conducted in Medline, PubMed, Cochrane Library, Embase, Scopus, and Web of Science databases up to December 2024. Studies included were randomized controlled trials (RCTs) comparing periodontal endoscope-assisted subgingival debridement (EASD) with repeated root surface debridement (RSD) and access flap periodontal surgery (AFPS). Data extraction and risk of bias assessment were performed independently by two reviewers.

resultsFive RCTs were included, involving 155 subjects and 4072 sites. EASD showed a significantly higher periodontal probing depth (PPD) reduction compared to repeated RSD, with a weighted mean difference (WMD) of 0.5 mm (95% CI: 0.19-0.81) at 3-month postoperation. At 6-month postoperation, the WMD of PPD and clinical attachment level (CAL) changes were 0.84 mm (95% CI: 0.60-1.09) and 0.89 mm (95% CI: 0.45-1.34), respectively, in favor of EASD. EASD showed a significantly higher prevalence ratio (20%) of pocket resolution (PPD ≤ 4 mm) compared to repeated RSD at 6-month postoperation. No significant differences were observed between EASD and AFPS in the changes of CAL, PPD and prevalence of pocket resolution (PPD ≤ 4 mm). The overall certainty of the evidence was deemed to be "low" for EASD versus repeated RSD comparisons and "moderate" for EASD versus AFPS comparisons.

conclusionsEASD demonstrated superior clinical outcomes compared to repeated RSD in managing residual periodontal pockets. Further high-quality research is necessary to validate these findings and explore the long-term benefits of EASD.

Indexed as

DebridementEndoscopyPeriodontal DebridementPeriodontal PocketPeriodontitisSurgical FlapsHumansRandomized Controlled Trials as TopicTooth RootTreatment Outcomeendoscopesmeta‐analysisperiodontal debridementperiodontitissystematic review

Identifiers

PMID40743404
PMCPMC12312801

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.