Evidence map›Paper›PMID 40743289›Full record

Observational studyPacing and clinical electrophysiology : PACE2025

Joint Pacing and Vascular Intervention for the Management of Cardiac Device Associated Central Venous Obstruction.

Nadeev Wijesuriya, Helen Sinabulya, Helena Johann-Meyer, Keisha Kellman, Felicity de Vere, Sandra Howell, Alphonsus Liew, Paolo Bosco, Steven A Niederer, Stephen Black and 1 more

Abstract readObservational Study
In one paragraph

Observational study in Pacing and clinical electrophysiology : PACE, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nadeev WijesuriyaKing's College London, London, UK.ORCID 0000-0001-7893-0708
Helen SinabulyaGuy's and St Thomas's NHS Foundation Trust, London, UK.
Helena Johann-MeyerGuy's and St Thomas's NHS Foundation Trust, London, UK.
Keisha KellmanGuy's and St Thomas's NHS Foundation Trust, London, UK.
Felicity de VereKing's College London, London, UK.
Sandra HowellKing's College London, London, UK.
Alphonsus LiewKing's College London, London, UK.
Paolo BoscoGuy's and St Thomas's NHS Foundation Trust, London, UK.
Steven A NiedererImperial College, London, UK.
Stephen BlackGuy's and St Thomas's NHS Foundation Trust, London, UK.
Christopher A RinaldiKing's College London, London, UK.ORCID 0000-0002-3930-1957

Funding

Using Atrial Mechanics To Identify Fibrosis In Patients with Atrial FibrillationR01HL152256 · NHLBI · STANFORD UNIVERSITY · PI ENNIS, DANIEL B · 2020 to 2023
$2.8M
British Heart Foundation (BHF) FS/CRTF/22/24362EBR SystemsEuropean Research Council ERC PREDICT-HF 864055NHLBI NIH HHS R01 HL152256the BHF PG/15/91/31812 PG/13/37/30280 SP/18/6/33805UK Engineering and Physical Sciences Research Council EP/M012492/1 NS/A000049/1 EP/P01268X/1US National Institutes of Health R01-HL152256Wellcome/EPSRC Centre for Medical Engineering WT203148/Z/16/ZWellcome Trust
6 · The paper itself

Abstract

BACKGROUND AND

aimsCentral venous obstruction (CVO) increases the complexity of pacing interventions, whether it be with device-associated symptomatic superior vena cava syndrome (SVCS), or by impeding new implants. Endovascular treatment involves the joint expertise of both cardiac pacing and vascular specialists. We report the outcomes of such procedures at our institution.

methodsA single-center retrospective observational study, examining outcomes of joint pacing-vascular procedures for CVO. Cases were screened from an existing institutional database.

resultsThere were 19 total cases. Two were new device implants where the novel "inside-out" procedure was utilized to establish access in SVCS, both with no complications. The remainder (n = 17) were transvenous lead extractions plus attempted recanalization of CVO using venoplasty with or without stenting. Transvenous devices were re-implanted in eight patients. Complete procedure success rate was 84%. There were two cases of pericardial effusion requiring pericardiocentesis, resulting in procedure abandonment. There was no in-hospital mortality and no cases of emergency sternotomy. Over mean follow-up of 28 months, 2/6 patients receiving venoplasty (33%) and 2/8 patients receiving stenting (25%) required re-intervention for symptomatic restenosis. Of the patients who were not re-implanted with a transvenous device following initially successful endovascular intervention (6/14), none had recurrence over the follow-up period.

conclusionPacing interventions in SVCS carry a significant risk profile, requiring management by experienced operators in high-volume centers to maximize safety. Endovascular interventions have a significant recurrence rate, with up-front stenting potentially being superior. Our data suggests that those without re-implantation of transvenous leads may have better long term outcomes.

Indexed as

Defibrillators, ImplantableEndovascular ProceduresPacemaker, ArtificialSuperior Vena Cava SyndromeAgedAged, 80 and overDevice RemovalFemaleHumansMaleMiddle AgedRetrospective StudiesStentsTreatment Outcomeextractionpacemakersuperior vena cava syndromevenoplastyvenous obstructionvenous stenting

Identifiers

PMID40743289
PMCPMC12439234

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.