ReviewPLoS neglected tropical diseases2025
Comprehensive analysis of Toxoplasma gondii migration routes and tissue dissemination in the host.
Review in PLoS neglected tropical diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Clinical and imaging characterization of ocular toxoplasmosis in a Central-West Brazilian population.International ophthalmology · 2026Article
- The Effect of Curcumin on Chronic Toxoplasma gondii Infection in the Testes of BALB/c Mice.Acta parasitologica · 2026Article
- Lipidomic Profiling of Colonic Contents in Mice with AcuteMicroorganisms · 2026Article
- Development and evaluation of recombinant dense granule 14 for serological diagnosis of Toxoplasma gondii infection in domestic cats.Scientific reports · 2026Article
- Investigating the prevalence of Toxoplasma gondii infection in Parkinson's disease patients and its association with disease severity: a case-control study.BMC infectious diseases · 2026Article
- The eye as a gateway to the brain: mechanisms of ocular neuroinvasion by parasitic pathogens.GMS hygiene and infection control · 2026Article
- Dense granule proteins: key mediators ofFrontiers in medicine · 2026Review
- Free GPIs and Comparison of GPI Structures Among Species.International journal of molecular sciences · 2025Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Toxoplasma gondii is a highly adaptable intracellular parasite capable of infecting a wide range of warm-blooded animals, including humans. Following the ingestion of cysts and oocysts, the parasites rapidly emerge and transmigrate through the bloodstream, initiating a complex infection process. Despite reports on the parasite's dissemination, the mechanisms behind its migration remain unclear. Recent advances using innovative 3D models and various host systems are beginning to shed light on the migratory routes and strategies employed by T. gondii. This review compiles current knowledge on the migration and dissemination of T. gondii, from its initial interactions in the gut to its invasion of immune-privileged organs. This review provides a comprehensive understanding of how T. gondii establishes its infection crossing the most impermeable biological barriers within the host.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.