Evidence map›Paper›PMID 40742769›Full record

Trial reportRehabilitation psychology2026

Reducing burden and anxiety for caregivers of veterans with traumatic brain injury and dementia: Randomized controlled trial of the resources for enhancing all caregivers' health-Hope intervention.

Linda O Nichols, Jennifer Martindale-Adams, Ronald T Seel, Jeffrey K Zuber, Robert Perera, Paul B Perrin

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Rehabilitation psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Linda O NicholsCaregiver Center, Lt. Col. Luke Weathers, Jr. Veterans Affairs Medical Center.
Jennifer Martindale-AdamsCaregiver Center, Lt. Col. Luke Weathers, Jr. Veterans Affairs Medical Center.
Ronald T SeelDepartment of Physical Medicine and Rehabilitation, School of Medicine, Center for Rehabilitation Science and Engineering, Virginia Commonwealth University.
Jeffrey K ZuberCaregiver Center, Lt. Col. Luke Weathers, Jr. Veterans Affairs Medical Center.
Robert PereraDepartment of Biostatistics, School of Public Health, Virginia Commonwealth University.
Paul B PerrinSchool of Data Science, University of Virginia.ORCID 0000-0003-2070-215X

Funding

U.S. Army Medical Research and Development Command; Military Operational Medicine Research ProgramUS Department of Defense; Congressionally Directed Medical Research ProgramsVA VA 999999
6 · The paper itself

Abstract

PURPOSE/

objectiveCaregivers of veterans with comorbid traumatic brain injury (TBI) and dementia face many challenges managing their loved ones' neurobehavioral functioning and, importantly, their own well-being. This study developed and tested Resources for Enhancing All Caregivers' Health (REACH) Hope, which provides caregivers with one-on-one telehealth education, support, skills building, and personalized digital information.

methodCaregivers (

resultsREACH Hope reduced burden and anxiety for caregivers with moderate to high levels of burden and anxiety compared to the waitlist group. Caregivers with ZBI-12 scores ≥ 21 had increasing treatment benefits with higher burden. Caregivers with Generalized Anxiety Disorder-7 scores ≥ 13 showed the same pattern for higher anxiety levels. There were no significant treatment group effects for depression, self-efficacy, or veteran safety.

conclusionThis is the first clinical trial to evaluate the efficacy of a telehealth intervention for caregivers of veterans with both TBI and dementia. REACH Hope represents the first evidence-based intervention of its kind and one that warrants further study and implementation. (PsycInfo Database Record (c) 2026 APA, all rights reserved).

Indexed as

AnxietyBrain Injuries, TraumaticCaregiversDementiaVeteransAdultAgedCost of IllnessFemaleHumansMaleMental Health TeletherapyMiddle AgedSelf EfficacyTelemedicine

Identifiers

PMID40742769
PMCPMC12483318

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.